RELATIONSHIP BETWEEN THE CLINICOPATHOLOGIC FEATURES OF GASTRIC ADENOCARCINOMA AND SERUM CANCENTRATION OF AFP

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HAKAK J.B.; NIK SHOAR M.R.; AZADEH P.; FOUDAZI M.; KHODDAMI M.; VELAEI N.

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Journal: Researcher Bulletin of Medical Sciences Year:2004 | Volume:9 | Issue:4 (40) Page(s): 221-224

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Title

RELATIONSHIP BETWEEN THE CLINICOPATHOLOGIC FEATURES OF GASTRIC ADENOCARCINOMA AND SERUM CANCENTRATION OF AFP

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Keywords

ALFA FETO PROTEIN (AFP)Q3

GASTRIC CANCERQ4

PATHOLOGIC FEATURESQ4

RESPECTABILITYQ4

PERITONEAL INVOLVMENTQ4

Abstract

Background: Role of serum AFP as a tumor marker and prognostic factors in gastric adenocarcinoma is doubtful. This study was performed to determine the relationship between clinicopathological features of patients with non metastaic GASTRIC CANCER and serum AFP in Imam Hossein hospital and Khatam–al–anbia hospital during period of 1381-1383. Materials and methods: In this cross-sectional study, all of the patients with non metastatic gastric adenocarcinoma cancer were studied and their clinicopathological feature of disease (liver metastasis, peritoneal seeding pathologic stage, RESPECTABILITY) and serum AFP were determined. Values more than 20IU/ml were considered as high serum AFP (or abnormal) and clinicpathologic features of disease evaluated statistically. Results: From 96 patients with GASTRIC CANCER (non metastatic) only 9 patient had abnormal AFP. There was a significant relationship between RESPECTABILITY and peritoneal seeding with elevation of AFP (p<0.05), but not between AFP elevation with patient’s background. Conclusion: According to this study, AFP is an important factor to diagnosis the non-metastatic gastric adenocarcinoma, Since this test is feasible and low price ,it is suggested to be done in these patients. Because, RESPECTABILITY and peritoneal seeding are unrespectable in patients with abnormal AFP, we recommend to do laparascopy before surgery to prevent unnecessary surgery and propose connection between AFP value, peritoneal seeding and RESPECTABILITY in analytical research.

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References

EPIDEMIOLOGICAL STUDY OF 17606 CASES OF REGISTERED CANCERS AT DEPARTMENT OF RADIATION ONCOLOGY JORJANI HOSPITAL

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APA: Copy

HAKAK, J.B., NIK SHOAR, M.R., AZADEH, P., FOUDAZI, M., KHODDAMI, M., & VELAEI, N.. (2004). RELATIONSHIP BETWEEN THE CLINICOPATHOLOGIC FEATURES OF GASTRIC ADENOCARCINOMA AND SERUM CANCENTRATION OF AFP. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 9(4 (40)), 221-224. SID. https://sid.ir/paper/18600/en

Vancouver: Copy

HAKAK J.B., NIK SHOAR M.R., AZADEH P., FOUDAZI M., KHODDAMI M., VELAEI N.. RELATIONSHIP BETWEEN THE CLINICOPATHOLOGIC FEATURES OF GASTRIC ADENOCARCINOMA AND SERUM CANCENTRATION OF AFP. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2004;9(4 (40)):221-224. Available from: https://sid.ir/paper/18600/en

IEEE: Copy

J.B. HAKAK, M.R. NIK SHOAR, P. AZADEH, M. FOUDAZI, M. KHODDAMI, and N. VELAEI, “RELATIONSHIP BETWEEN THE CLINICOPATHOLOGIC FEATURES OF GASTRIC ADENOCARCINOMA AND SERUM CANCENTRATION OF AFP,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 9, no. 4 (40), pp. 221–224, 2004, [Online]. Available: https://sid.ir/paper/18600/en

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