CORRELATION BETWEEN ER, PR, HER2 RECEPTORS AND PROGNOSTIC FACTORS IN BREAST CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MIRZAEI HAMID REZA; SABAHAT A.; NASR ELAHI F.; MOHAMMADI YEGANEH L.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Researcher Bulletin of Medical Sciences Year:2010 | Volume:15 | Issue:4 (76) Page(s): 152-156

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,805

Download:

Cites:

Information Journal Paper

Title

CORRELATION BETWEEN ER, PR, HER2 RECEPTORS AND PROGNOSTIC FACTORS IN BREAST CANCER

Author(s)

MIRZAEI HAMID REZA | SABAHAT A. | NASR ELAHI F. | MOHAMMADI YEGANEH L. | Issue Writer Certificate

Keywords

RECEPTORSQ3

PROGESTERONEQ3

RECEPTORSQ3

ESTROGENQ2

HER2 RECEPTORSQ2

BREAST NEOPLASMSQ2

PROGNOSTIC FACTORSQ2

Abstract

Background and Aim: Studies have shown that breast cancer patients who have ESTROGEN receptor (ER) or PROGESTERONE receptor (PR) positive tumors have lower risks of mortality and better response to treatment compared to women with ER and/ or PR negative breast tumors. However, few studies have been performed about these factors and their relation with demographic or clinical characteristics in Iran. So we decided to evaluate the correlation between ER, PR and Human epidermal growth factor 2 (HER-2) with age, tumor size, tumor histological grade and lymph node metastasis as PROGNOSTIC FACTORS in breast cancer.Materials and Methods: In this cross sectional study, 138 patients with invasive ductal breast carcinoma who were admitted in Shohadaye Tajrish hospital during 2004-2005 were studied and all information was gathered from patients’ medical records.Results: Statistically significant correlation between ER, PR, and HER-2 RECEPTORS with age, tumor size and lymph node metastasis was not observed. Also correlation between ER, PR and HER-2 RECEPTORS with tumor grade was not significant. But there was significant correlation between HER-2 RECEPTORS and tumor grade (P<0.05). Correlation between ER and PR with HER-2 RECEPTORS was not significant. Also there was not a significant correlation between Triple Negative tumors and age, tumor size, tumor grade, and lymph node involvement.Conclusion: It seems that patients with HER2 positive tumors tend to face higher grade tumors and metastasis, besides; maybe they face an increased risk of mortality.

Cites

IMMUNOHISTOCHEMICAL ASSESSMENT OF ER AND PR STATUS IN TISSUE TUMORS OF BREAST CANCER PATIENTS AND THEIR RELATION WITH PROLIFERATION AND TUMOR GRADE

References

Cite

APA: Copy

MIRZAEI, HAMID REZA, SABAHAT, A., NASR ELAHI, F., & MOHAMMADI YEGANEH, L.. (2010). CORRELATION BETWEEN ER, PR, HER2 RECEPTORS AND PROGNOSTIC FACTORS IN BREAST CANCER. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 15(4 (76)), 152-156. SID. https://sid.ir/paper/18649/en

Vancouver: Copy

MIRZAEI HAMID REZA, SABAHAT A., NASR ELAHI F., MOHAMMADI YEGANEH L.. CORRELATION BETWEEN ER, PR, HER2 RECEPTORS AND PROGNOSTIC FACTORS IN BREAST CANCER. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2010;15(4 (76)):152-156. Available from: https://sid.ir/paper/18649/en

IEEE: Copy

HAMID REZA MIRZAEI, A. SABAHAT, F. NASR ELAHI, and L. MOHAMMADI YEGANEH, “CORRELATION BETWEEN ER, PR, HER2 RECEPTORS AND PROGNOSTIC FACTORS IN BREAST CANCER,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 15, no. 4 (76), pp. 152–156, 2010, [Online]. Available: https://sid.ir/paper/18649/en

Related Journal Papers