MICRORNAS IN MULTIPLE SCLEROSIS

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PAHLEVAN KAKHKI M.; NIKRAVESH A.; RAKHSHI N.; HEIDARY M.

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Journal Paper

Paper Information

Journal: JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES Year:2013 | Volume:5 | Issue:1 Page(s): 185-194

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Information Journal Paper

Title

MICRORNAS IN MULTIPLE SCLEROSIS

Author(s)

PAHLEVAN KAKHKI M. | NIKRAVESH A. | RAKHSHI N. | HEIDARY M. | Issue Writer Certificate

Keywords

MICRORNASQ2

MULTIPLE SCLEROSISQ1

BIOMARKERQ2

Abstract

Background & Objectives: MULTIPLE SCLEROSIS (MS) is a potentially devastating disease in the central nervous system with an unknown etiology. Many epidemiologic and genetic studies are revealed that both genetic and environment can influence the susceptibility of MS. When MICRORNAS are introduced to molecular genetic world, they could establish their position in genetic studies. MiRNAs are small (19-24 nucleotides) noncoding RNAs. Here, we are trying to introduce the role of miRNAs in MS and their potentials to serve as BIOMARKERs.Material & Methods: In this study we reviewed some different articles in a 10-years period about the role of miRNAs in MS.Then we selected the specific keywords and the most recent data were collected in this field.Results: The results show that many studies are performed on the role of miRNAs in various aspects of miRNAs in MS. In addition, miRNAs can be involved in the pathogenesis of MS, as well as they have some new therapeutic potential for MS through the gene expression regulation.Conclusion: Our results suggest that beside the role of miRNAs in MS pathogenesis, they have some therapeutic potential for MS.As well as, they can serve as BIOMARKERs to evaluate disease progression and therapeutic efforts.

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APA: Copy

PAHLEVAN KAKHKI, M., NIKRAVESH, A., RAKHSHI, N., & HEIDARY, M.. (2013). MICRORNAS IN MULTIPLE SCLEROSIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, 5(1), 185-194. SID. https://sid.ir/paper/187089/en

Vancouver: Copy

PAHLEVAN KAKHKI M., NIKRAVESH A., RAKHSHI N., HEIDARY M.. MICRORNAS IN MULTIPLE SCLEROSIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2013;5(1):185-194. Available from: https://sid.ir/paper/187089/en

IEEE: Copy

M. PAHLEVAN KAKHKI, A. NIKRAVESH, N. RAKHSHI, and M. HEIDARY, “MICRORNAS IN MULTIPLE SCLEROSIS,” JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, vol. 5, no. 1, pp. 185–194, 2013, [Online]. Available: https://sid.ir/paper/187089/en

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