THE EFFECT OF GRAPE SEED EXTRACT ON LIPID PROFILE ANDBLOOD PRESSURE OF PATIENTS WITH HYPERLIPIDEMIA: ARANDOMIZED DOUBLE BLIND CLINICAL TRIAL STUDY

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MOHAMMADIPOUR F.; CHERAGHIPOUR J.

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Journal: Nursing And Midwifery Journal Year:2016 | Volume:14 | Issue:1 (78) Page(s): 1-9

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Title

THE EFFECT OF GRAPE SEED EXTRACT ON LIPID PROFILE ANDBLOOD PRESSURE OF PATIENTS WITH HYPERLIPIDEMIA: ARANDOMIZED DOUBLE BLIND CLINICAL TRIAL STUDY

Author(s)

MOHAMMADIPOUR F. | CHERAGHIPOUR J. | Issue Writer Certificate

Keywords

GRAPE SEED EXTRACTQ2

HYPERLIPIDEMIASQ2

BLOOD PRESSUREQ2

CARDIO METABOLIC RISKQ2

CVD RISKFACTORSQ2

Abstract

Background & Aims: Hyperlipidemia is a risk factor that caused and exacerbated cardiovasculardisease. There are several different diets and chemical and herbal medicines for correction and reductionof hyperlipidemia. This study investigated the effect of GRAPE SEED EXTRACT on lipid profile and bloodpressure in patients with borderline hyperlipidemia.Materials & Methods: This study was a randomized double-blind clinical trial with before and afterdesign, in which 88 patients with borderline hyperlipidemia were matched by their age, sex, blood lipidprofile, and they were randomly allocated to one of the two intervention groups (2 capsules containing 100 mg of GRAPE SEED EXTRACT) or control (2 placebo). They consumed drug or placebo for 6 weeks. Tocontrol the effect of diet on measuring variables three consecutive days before the start ofsupplementation and two days at the end of the study, 24 Hour Reminder Food questionnaire wascompleted by the subjects. Lipid profile and BLOOD PRESSURE were analyzed before and after treatment.Results: In the intervention group oxidized LDL was significantly reduced and HDL was increased (p<0.05), but no significant change was observed in BLOOD PRESSURE compared to control group.Conclusion: Based on the good effects of GRAPE SEED EXTRACT in reducing oxidized LDL and increasingHDL, it can be suggested that this extract could be used as an adjunct in the treatment of hyperlipidemicpatients.

Cites

EFFECT OF RAISIN CONSUMPTION ON SOME COAGULATION FACTORS AND TOTAL SERUM ANTIOXIDANT CAPACITY IN HYPERLIPIDEMIC PATIENTS: A RANDOMIZED CLINICAL CONTROLLED TRIA

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APA: Copy

MOHAMMADIPOUR, F., & CHERAGHIPOUR, J.. (2016). THE EFFECT OF GRAPE SEED EXTRACT ON LIPID PROFILE ANDBLOOD PRESSURE OF PATIENTS WITH HYPERLIPIDEMIA: ARANDOMIZED DOUBLE BLIND CLINICAL TRIAL STUDY. JOURNAL OF URMIA NURSING AND MIDWIFERY FACULTY, 14(1 (78)), 1-9. SID. https://sid.ir/paper/190955/en

Vancouver: Copy

MOHAMMADIPOUR F., CHERAGHIPOUR J.. THE EFFECT OF GRAPE SEED EXTRACT ON LIPID PROFILE ANDBLOOD PRESSURE OF PATIENTS WITH HYPERLIPIDEMIA: ARANDOMIZED DOUBLE BLIND CLINICAL TRIAL STUDY. JOURNAL OF URMIA NURSING AND MIDWIFERY FACULTY[Internet]. 2016;14(1 (78)):1-9. Available from: https://sid.ir/paper/190955/en

IEEE: Copy

F. MOHAMMADIPOUR, and J. CHERAGHIPOUR, “THE EFFECT OF GRAPE SEED EXTRACT ON LIPID PROFILE ANDBLOOD PRESSURE OF PATIENTS WITH HYPERLIPIDEMIA: ARANDOMIZED DOUBLE BLIND CLINICAL TRIAL STUDY,” JOURNAL OF URMIA NURSING AND MIDWIFERY FACULTY, vol. 14, no. 1 (78), pp. 1–9, 2016, [Online]. Available: https://sid.ir/paper/190955/en

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