EFFECT OF THE EXTRACT OF HYPERICUM PERFORATUM ON DIGESTIVE ORGANS MORPHOMETRY IN WISTAR RATS

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MODHEJ MARYAM; TABATABAEE VAKILI SALEH; SARI MOHSEIN; SALARI SOMAYEH; MANSURI ESRAFIL

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Journal: JOURNAL OF HERBAL DRUGS Year:2013 | Volume:3 | Issue:4 Page(s): 239-242

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Title

EFFECT OF THE EXTRACT OF HYPERICUM PERFORATUM ON DIGESTIVE ORGANS MORPHOMETRY IN WISTAR RATS

Author(s)

Keywords

HYPERICUM PERFORATUMQ2

MORPHOMETRICQ2

DIGESTIVE ORGANSQ2

RATQ2

Abstract

Background & Aim: St John's wort (HYPERICUM PERFORATUM L.) contains hypericin and hyperforin as the main components of the extract that binds with GABA and sigma opioid receptors. This herb has many pharmacological effects, including analgesic, sedative, soothing, antispasmodic, anticonvulsant, anti-depressant, and anti-bacteria. In this study examined the effect of two concentrations of HYPERICUM PERFORATUM extract on DIGESTIVE ORGANS MORPHOMETRIC in male Wistar RATs.Experimental: Among the 54 RATs tested with six repetitions, effect of HYPERICUM PERFORATUM extract was assessed in three groups. Experimental treatments were control (receiving water), groups two and three that received HYPERICUM PERFORATUM extract (250 and 500 mg /kg.bw) respectively. RATs were treated with HYPERICUM PERFORATUM for30 days, through the Gavage method.Results & Discussion: Results indicated that big intestine weight in the 250 mg/kg.bw HYPERICUM PERFORATUM treatment significantly was more than the control group (p£0.05), and also the length of big intestine was taller in 250 and 500 mg/kg.bw treatments than control group (p£0.05).Recommended application: According to results, the extract of HYPERICUM PERFORATUM can use for weight increasing.

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APA: Copy

MODHEJ, MARYAM, TABATABAEE VAKILI, SALEH, SARI, MOHSEIN, SALARI, SOMAYEH, & MANSURI, ESRAFIL. (2013). EFFECT OF THE EXTRACT OF HYPERICUM PERFORATUM ON DIGESTIVE ORGANS MORPHOMETRY IN WISTAR RATS. JOURNAL OF HERBAL DRUGS, 3(4), 239-242. SID. https://sid.ir/paper/193842/en

Vancouver: Copy

MODHEJ MARYAM, TABATABAEE VAKILI SALEH, SARI MOHSEIN, SALARI SOMAYEH, MANSURI ESRAFIL. EFFECT OF THE EXTRACT OF HYPERICUM PERFORATUM ON DIGESTIVE ORGANS MORPHOMETRY IN WISTAR RATS. JOURNAL OF HERBAL DRUGS[Internet]. 2013;3(4):239-242. Available from: https://sid.ir/paper/193842/en

IEEE: Copy

MARYAM MODHEJ, SALEH TABATABAEE VAKILI, MOHSEIN SARI, SOMAYEH SALARI, and ESRAFIL MANSURI, “EFFECT OF THE EXTRACT OF HYPERICUM PERFORATUM ON DIGESTIVE ORGANS MORPHOMETRY IN WISTAR RATS,” JOURNAL OF HERBAL DRUGS, vol. 3, no. 4, pp. 239–242, 2013, [Online]. Available: https://sid.ir/paper/193842/en

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