PRIMARY DNA DAMAGE IN TAXI DRIVERS WITH TRAFFIC RELATED AIR POLLUTION EXPOSURE: RESULTS OF COMET ASSAY TEST

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REZAEI HACHESU VIDA; NADERYAN FELI SHADI; AZIMI MOHAMMAD; MEHRPARVAR AMIR HOUSHANG; ZAVAR REZA JAVAD; KARGAR SHOUROKI FATEMEH; ZAREH SAKHVIDI MOHAMMAD JAVAD

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Journal: Tibbi- i- kar Year:2017 | Volume:9 | Issue:2 Page(s): 1-9

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Title

PRIMARY DNA DAMAGE IN TAXI DRIVERS WITH TRAFFIC RELATED AIR POLLUTION EXPOSURE: RESULTS OF COMET ASSAY TEST

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Keywords

DNA DAMAGEQ1

COMET ASSAYQ1

TAXI DRIVERQ1

Abstract

Introduction: Several studies have shown that DNA DAMAGEs increase the risk of diseases such as cancer. One of the tests that used to assess the damage to DNA is COMET ASSAY. In this study, the initial damage caused by exposure to traffic-related air pollution was studied.Methods: In this analytic cross sectional study, 104 TAXI DRIVERs were selected in Yazd, Iran. Peripheral blood sampling was performed. Microscopic analysis was performed under 400 magnification fluorescent microscope. Imagej software was used for image analysis. Data were tested by Kolmogorov–Smirnov test and Mann–Whitney U-test. Correlation analysis was performed.Results: In this study, all the participants were male. The mean±SD of the age and experience of the study population was 45.8±11.59 and 11.31±8.67 years, respectively. There was no significant difference between smokers and non-smokers in comet parameters. There was no significant correlation between Comet parameters and workload. There was direct and significant correlation between all parameters of comet.There was a significant correlation between tail intensity parameter and age after elimination of the confounding the effect of smoking.Conclusions: In the results of the present study, there was not shown any genetic damages in TAXI DRIVERs exposed to the traffic related air pollution. Also, there is no significant relationship between these damages and smoking.

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References

CYTOKINESIS BLOCKED MICRONUCLEUS ASSAY FOR EVALUATION OF CHROMOSOMAL BREAKS IN ESOPHAGEAL CANCER

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APA: Copy

REZAEI HACHESU, VIDA, NADERYAN FELI, SHADI, AZIMI, MOHAMMAD, MEHRPARVAR, AMIR HOUSHANG, ZAVAR REZA, JAVAD, KARGAR SHOUROKI, FATEMEH, & ZAREH SAKHVIDI, MOHAMMAD JAVAD. (2017). PRIMARY DNA DAMAGE IN TAXI DRIVERS WITH TRAFFIC RELATED AIR POLLUTION EXPOSURE: RESULTS OF COMET ASSAY TEST. OCCUPATIONAL MEDICINE, 9(2), 1-9. SID. https://sid.ir/paper/207014/en

Vancouver: Copy

REZAEI HACHESU VIDA, NADERYAN FELI SHADI, AZIMI MOHAMMAD, MEHRPARVAR AMIR HOUSHANG, ZAVAR REZA JAVAD, KARGAR SHOUROKI FATEMEH, ZAREH SAKHVIDI MOHAMMAD JAVAD. PRIMARY DNA DAMAGE IN TAXI DRIVERS WITH TRAFFIC RELATED AIR POLLUTION EXPOSURE: RESULTS OF COMET ASSAY TEST. OCCUPATIONAL MEDICINE[Internet]. 2017;9(2):1-9. Available from: https://sid.ir/paper/207014/en

IEEE: Copy

VIDA REZAEI HACHESU, SHADI NADERYAN FELI, MOHAMMAD AZIMI, AMIR HOUSHANG MEHRPARVAR, JAVAD ZAVAR REZA, FATEMEH KARGAR SHOUROKI, and MOHAMMAD JAVAD ZAREH SAKHVIDI, “PRIMARY DNA DAMAGE IN TAXI DRIVERS WITH TRAFFIC RELATED AIR POLLUTION EXPOSURE: RESULTS OF COMET ASSAY TEST,” OCCUPATIONAL MEDICINE, vol. 9, no. 2, pp. 1–9, 2017, [Online]. Available: https://sid.ir/paper/207014/en

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