COMPARISON OF ANALGESIC EFFECT OF INTRAVENOUS PARACETAMOL PLUS MEPERIDINE AND MEPEREDINE ALONE ON POSTOPERATIVE PAIN AFTER ELECTIVE CESAREAN

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AMRIMALEH PARVIZ; ALIJANPOUR EBRAHIM; ZABIHI ALI; ATTARZADEH HASAN; SHIRKHANI ZIBA; REZAEE BAHAREH; REZAEE BENAFSHEH

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Journal: Journal of Anesthesiology and Pain Year:2013 | Volume:4 | Issue:1 Page(s): 1-7

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Title

COMPARISON OF ANALGESIC EFFECT OF INTRAVENOUS PARACETAMOL PLUS MEPERIDINE AND MEPEREDINE ALONE ON POSTOPERATIVE PAIN AFTER ELECTIVE CESAREAN

Author(s)

Keywords

CESAREAN SECTIONQ3

POST OPERATIVE PAINQ3

MEPERIDINEQ3

PARACETAMOLQ2

Abstract

Aim and Background: Effective postoperative pain control is very important. PARACETAMOL is a non-opioid analgesic drug with less side effects. At this study, we compare analgesic effect of PARACETAMOL plus MEPERIDINE and MEPERIDINE alone on postoperative cesarean.Methods and Materials: This double blind randomized clinical trial was conducted on 70 pregnant undergoing elective CESAREAN SECTION under Spinal Anesthesia. They were randomly divided into two equal groups. The first group received 1g intravenous PARACETAMOL, and the 2nd group received 25 mg intravenous MEPERIDINE15 minutes before the end of operation. The first group received infusion of 100 ml (1gr) PARACETAMOL and the 2nd group received 100 ml normal saline at 6, 12 and 18 hours after the end of operation. Patients’ pain assessment based on Visul Analogue Scales was done every 2 hour for 6 hours and then every 6 hour till 24 hours and recorded. When the patients’ VAS was more than 3, MEPERIDINE (25 mg) was administrated. Time to first MEPERIDINE injection after operation and the amount of meperedine was recorded.Findings: Time to the first MEPERIDINE injection after operation was hours in MEPERIDINE group and hours in PARACETAMOL group (p=0.005). Number of injections and total MEPERIDINE dose in PARACETAMOL group was significantly lower than another group (p<0.001).Conclusions: PARACETAMOL has a powerful analgesic effect on post CESAREAN SECTION pain and reduced total dose of Meperedin significantly.

Cites

Comparing the effects of Acetaminophen, Meperidine, and their combination on postoperative pain management in elective cesarean section

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APA: Copy

AMRIMALEH, PARVIZ, ALIJANPOUR, EBRAHIM, ZABIHI, ALI, ATTARZADEH, HASAN, SHIRKHANI, ZIBA, REZAEE, BAHAREH, & REZAEE, BENAFSHEH. (2013). COMPARISON OF ANALGESIC EFFECT OF INTRAVENOUS PARACETAMOL PLUS MEPERIDINE AND MEPEREDINE ALONE ON POSTOPERATIVE PAIN AFTER ELECTIVE CESAREAN. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 4(1), 1-7. SID. https://sid.ir/paper/216285/en

Vancouver: Copy

AMRIMALEH PARVIZ, ALIJANPOUR EBRAHIM, ZABIHI ALI, ATTARZADEH HASAN, SHIRKHANI ZIBA, REZAEE BAHAREH, REZAEE BENAFSHEH. COMPARISON OF ANALGESIC EFFECT OF INTRAVENOUS PARACETAMOL PLUS MEPERIDINE AND MEPEREDINE ALONE ON POSTOPERATIVE PAIN AFTER ELECTIVE CESAREAN. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2013;4(1):1-7. Available from: https://sid.ir/paper/216285/en

IEEE: Copy

PARVIZ AMRIMALEH, EBRAHIM ALIJANPOUR, ALI ZABIHI, HASAN ATTARZADEH, ZIBA SHIRKHANI, BAHAREH REZAEE, and BENAFSHEH REZAEE, “COMPARISON OF ANALGESIC EFFECT OF INTRAVENOUS PARACETAMOL PLUS MEPERIDINE AND MEPEREDINE ALONE ON POSTOPERATIVE PAIN AFTER ELECTIVE CESAREAN,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 4, no. 1, pp. 1–7, 2013, [Online]. Available: https://sid.ir/paper/216285/en

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