COMPARISON OF THE EFFECTS OF DIFFERENT DOSES OF KETAMINE PROPOFOL ON HAEMODYNAMIC CHANGES OF THE PATIENTS DURING INDUCTION OF ANESTHESIA

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KARIMAN MAJD M.H.; EMADI S.A.A.; NASIRI E.; FARZIN D.

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2006 | Volume:16 | Issue:54 Page(s): 7-13

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Title

COMPARISON OF THE EFFECTS OF DIFFERENT DOSES OF KETAMINE PROPOFOL ON HAEMODYNAMIC CHANGES OF THE PATIENTS DURING INDUCTION OF ANESTHESIA

Author(s)

KARIMAN MAJD M.H. | EMADI S.A.A. | NASIRI E. | FARZIN D. | Issue Writer Certificate

Keywords

PROPOFOLQ3

KETAMINEQ2

INDUCTION OF ANESTHESIA COMBINATIONQ3

Abstract

Background and purpose: The aim of this prospective, clinical trial study was to investigate whether the administration of different doses of KETAMINE before induction with PROPOFOL improves its associated haemodynamic PROPOFOL during induction and tracheal intubations.Materials and Methods: One hundered and thirty adult patients ASA I were randomly allocated to one of six groups to receive either PROPOFOL 2 mg/kg (n= 23), PROPOFOL 1.75 mg/kg with KETAMINE 0.25 mg/kg (n=21), PROPOFOL 1.5 mg/kg with KETAMINE 0.5 mg/kg (n=20), PROPOFOL 1.25 mg/kg with KETAMINE 0.75 mg/kg (n=21), PROPOFOL 1 mg/kg with KETAMINE 1 mg/kg (n=24), and KETAMINE group alone 2 mg/kg (n=21). KETAMINE was administered prior to induction with PROPOFOL, relaxant and tracheal intubations. Systolic, diastolic pressure and heart rate were automatically recorded before induction (Baseline), immediately after induction, and 1, 5 and 10 min after tracheal intubations by Armita devices.Results: Systolic, diastolic pressure and palse rate were not significantly different in different group's befor the induction. However theses difference were significant after the induction of anesthesia (P<0.001). The highest increase and decrease in blood pressure occurred in KETAMINE and PROPOFOL groups respectively. Haemodynamic stability was much better in patient's anesthetized using PROPOFOL plus 0.5 to 0.75 mg/kg KETAMINE.Conclusion: We conclude that the addition of KETAMINE 0.5 and 0.75 mg/kg improves haemodynamics when compared to KETAMINE 2 mg/kg alone or PROPOFOL 2 mg/kg during induction of anesthesia.

Cites

EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY

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APA: Copy

KARIMAN MAJD, M.H., EMADI, S.A.A., NASIRI, E., & FARZIN, D.. (2006). COMPARISON OF THE EFFECTS OF DIFFERENT DOSES OF KETAMINE PROPOFOL ON HAEMODYNAMIC CHANGES OF THE PATIENTS DURING INDUCTION OF ANESTHESIA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 16(54), 7-13. SID. https://sid.ir/paper/44846/en

Vancouver: Copy

KARIMAN MAJD M.H., EMADI S.A.A., NASIRI E., FARZIN D.. COMPARISON OF THE EFFECTS OF DIFFERENT DOSES OF KETAMINE PROPOFOL ON HAEMODYNAMIC CHANGES OF THE PATIENTS DURING INDUCTION OF ANESTHESIA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;16(54):7-13. Available from: https://sid.ir/paper/44846/en

IEEE: Copy

M.H. KARIMAN MAJD, S.A.A. EMADI, E. NASIRI, and D. FARZIN, “COMPARISON OF THE EFFECTS OF DIFFERENT DOSES OF KETAMINE PROPOFOL ON HAEMODYNAMIC CHANGES OF THE PATIENTS DURING INDUCTION OF ANESTHESIA,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 54, pp. 7–13, 2006, [Online]. Available: https://sid.ir/paper/44846/en

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