THE EFFECT OF ORAL GABAPENTIN ON TOURNIQUET-INDUCED HEMODYNAMIC CHANGES IN ORTHOPEDIC SURGERY UNDER GENERAL ANESTHESIA

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ROKHTABNAK FARANAK; KHOLDEBARIN ALIREZA; GHODRATI MOHAMMADREZA; POURNAJAFIAN ALIREZA; NIKZAD JAMNANI ALIREZA; KADKHODAZADEH MEHDI

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Journal: Journal of Anesthesiology and Pain Year:2013 | Volume:3 | Issue:3 Page(s): 169-174

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Title

THE EFFECT OF ORAL GABAPENTIN ON TOURNIQUET-INDUCED HEMODYNAMIC CHANGES IN ORTHOPEDIC SURGERY UNDER GENERAL ANESTHESIA

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Keywords

GABAPENTINQ2

TOURNIQUETQ2

BLOOD PRESSUREQ3

HEART RATEQ3

Abstract

Aim and Background: Prolonged use of TOURNIQUET for orthopedic surgery patient may cause a severe pain and hyperdynamic responses, which are mainly caused by CNS stimulus. We conducted this study to evaluate the effect of oral GABAPENTIN on TOURNIQUET-induced hemodynamic changes in orthopedic surgery under general anesthesia.Methods and Materials: Thirty six patients candidate for orthopedic surgery on lower limb under general anesthesia with TOURNIQUET inflation were enrolled. Patients were randomly allocated to oral GABAPENTIN 600 mg or placebo groups. We compared hemodynamic changes before and after inflation and defilation in both groups.Findings: After TOURNIQUET inflation, systolic and diastolic pressure in control group gradually raised. HEART RATE monitoring did not show significant differences between the two groups.Conclusions: Preoperative oral GABAPENTIN may prevent BLOOD PRESSURE increase in patients under general anesthesia with prolonged TOURNIQUET administration.

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APA: Copy

ROKHTABNAK, FARANAK, KHOLDEBARIN, ALIREZA, GHODRATI, MOHAMMADREZA, POURNAJAFIAN, ALIREZA, NIKZAD JAMNANI, ALIREZA, & KADKHODAZADEH, MEHDI. (2013). THE EFFECT OF ORAL GABAPENTIN ON TOURNIQUET-INDUCED HEMODYNAMIC CHANGES IN ORTHOPEDIC SURGERY UNDER GENERAL ANESTHESIA. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 3(3), 169-174. SID. https://sid.ir/paper/216353/en

Vancouver: Copy

ROKHTABNAK FARANAK, KHOLDEBARIN ALIREZA, GHODRATI MOHAMMADREZA, POURNAJAFIAN ALIREZA, NIKZAD JAMNANI ALIREZA, KADKHODAZADEH MEHDI. THE EFFECT OF ORAL GABAPENTIN ON TOURNIQUET-INDUCED HEMODYNAMIC CHANGES IN ORTHOPEDIC SURGERY UNDER GENERAL ANESTHESIA. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2013;3(3):169-174. Available from: https://sid.ir/paper/216353/en

IEEE: Copy

FARANAK ROKHTABNAK, ALIREZA KHOLDEBARIN, MOHAMMADREZA GHODRATI, ALIREZA POURNAJAFIAN, ALIREZA NIKZAD JAMNANI, and MEHDI KADKHODAZADEH, “THE EFFECT OF ORAL GABAPENTIN ON TOURNIQUET-INDUCED HEMODYNAMIC CHANGES IN ORTHOPEDIC SURGERY UNDER GENERAL ANESTHESIA,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 3, no. 3, pp. 169–174, 2013, [Online]. Available: https://sid.ir/paper/216353/en

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