PREOPERATIVE ORAL DEXTROMETHORPHAN VERSUS CLONIDINE TO PREVENT TOURNIQUET- INDUCED CARDIOVASCULAR RESPONSES IN ORTHOPEDIC PATIENTS UNDER GENERAL ANESTHESIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SAFAVI M.R.; HONARMAND A.; SARYAZDI H.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES Year:2007 | Volume:6 | Issue:3 (24) Page(s): 171-178

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

851

Download:

Cites:

Information Journal Paper

Title

PREOPERATIVE ORAL DEXTROMETHORPHAN VERSUS CLONIDINE TO PREVENT TOURNIQUET- INDUCED CARDIOVASCULAR RESPONSES IN ORTHOPEDIC PATIENTS UNDER GENERAL ANESTHESIA

Author(s)

SAFAVI M.R. | HONARMAND A. | SARYAZDI H. | Issue Writer Certificate

Keywords

CLONIDINEQ3

DEXTROMETHORPHANQ3

TOURNIQUET-INFLATIONQ3

HYPERTENSIONQ3

Abstract

Background and Objective: Both preoperative oral DEXTROMETHORPHAN (DM) and IV CLONIDINE attenuates arterial blood pressure and increases the heart rate during tourniquet inflation. Effect of preoperative oral CLONIDINE on these variables was not investigated. We designed this study to compare the effect of preoperative oral DM or CLONIDINE on hemodynamic changes during tourniquet inflation in patients undergoing lower limb surgery under general anesthesia.Materials and Methods: Seventhy-five patients were randomly assigned into three groups; DM (n= 25; DM 30 mg), CLONIDINE (n= 25; CLONIDINE 3 mg/kg), and control (n= 25; placebo) groups. DM, CLONIDINE, or placebo was given orally ninety minutes before induction of anesthesia. Systolic, Diastolic, Mean arterial blood pressure (SAP, DAP, MAP), and heart rate (HR) were measured at 0, 30, 45, 60 min after the start of tourniquet inflation, before tourniquet release (BTR), and 20 min after tourniquet deflation (20 ATR).Results: SAP, DAP, and MAP were significantly lower in the CLONIDINE group compared with control after 45, 60 min tourniquet inflation and at BTR (p<0.05). Twenty minutes after deflation, DAP and MAP in the control group was still increased significantly compared with the CLONIDINE group (P< 0.05).Conclusion: Preoperative oral CLONIDINE 3 mg/kg significantly prevented tourniquet-induced systemic arterial pressure increase in patients under general anesthesia better than oral DM.

Cites

No record.

References

No record.

Cite

APA: Copy

SAFAVI, M.R., HONARMAND, A., & SARYAZDI, H.. (2007). PREOPERATIVE ORAL DEXTROMETHORPHAN VERSUS CLONIDINE TO PREVENT TOURNIQUET- INDUCED CARDIOVASCULAR RESPONSES IN ORTHOPEDIC PATIENTS UNDER GENERAL ANESTHESIA. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 6(3 (24)), 171-178. SID. https://sid.ir/paper/71111/en

Vancouver: Copy

SAFAVI M.R., HONARMAND A., SARYAZDI H.. PREOPERATIVE ORAL DEXTROMETHORPHAN VERSUS CLONIDINE TO PREVENT TOURNIQUET- INDUCED CARDIOVASCULAR RESPONSES IN ORTHOPEDIC PATIENTS UNDER GENERAL ANESTHESIA. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2007;6(3 (24)):171-178. Available from: https://sid.ir/paper/71111/en

IEEE: Copy

M.R. SAFAVI, A. HONARMAND, and H. SARYAZDI, “PREOPERATIVE ORAL DEXTROMETHORPHAN VERSUS CLONIDINE TO PREVENT TOURNIQUET- INDUCED CARDIOVASCULAR RESPONSES IN ORTHOPEDIC PATIENTS UNDER GENERAL ANESTHESIA,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 6, no. 3 (24), pp. 171–178, 2007, [Online]. Available: https://sid.ir/paper/71111/en

Related Journal Papers