COMPARING THE ANALGESIC EFFECT PREGABALIN AND GABAPENTIN AS PREMEDICATION IN LAPAROSCOPIC PROCEDURES

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HASSANI VALLIOLLAH; IMANI FARNAD; ALIMIAN MAHZAD; ABDOLALIZADE MASOOME

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Journal: Journal of Anesthesiology and Pain Year:2012 | Volume:2 | Issue:6 Page(s): 30-36

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Title

COMPARING THE ANALGESIC EFFECT PREGABALIN AND GABAPENTIN AS PREMEDICATION IN LAPAROSCOPIC PROCEDURES

Author(s)

HASSANI VALLIOLLAH | IMANI FARNAD | ALIMIAN MAHZAD | ABDOLALIZADE MASOOME | Issue Writer Certificate

Keywords

GABAPENTINQ2

PREGABALINQ2

LAPAROSCOPIC SURGERYQ2

VASQ3

Abstract

Aim and Background: LAPAROSCOPIC SURGERY is associated with post operative pain. optimal pain treatment with minimal side effects is essential for early recovery and mobility in patients undergoing LAPAROSCOPIC SURGERY. we compared the analgesic effect PREGABALIN and GABAPENTIN with different doses in these surgical procedures.Methods and Materials: In a randomized, double blind, ninety patients were allocated to either Group A PREGABALIN 300mg, GroupB GABAPENTIN 600mg and Group C GABAPENTIN 900mg .these were administered 1 h before operation. General anesthesia was performed. we collected data on pain intensity through Visual Analogue Scale (VAS) in recovery, 6, 24 h after operation. Consumption of supp Diclofenac was recorded. p<0.05 was considered statistically significant.Findings: PREGABALIN 300 mg was significantly more effective in reducing post operative pain up to 24 hours following the surgery (p<0.001). Furthermore, the amount of analgesic consumption was less in the PREGABALIN group (p<0.001). Consumption analgesic and VAS were more than the other groups in patient who receive GABAPENTIN 600 mg.Conclusions: Our finding showed that single dose of PREGABALIN 300mg oral is more effective than Gabapatin on the management of postoperative pain following abdominal LAPAROSCOPIC SURGERY. And PREGABALIN resulted in reduction in 24 h postoperative analgesic requirements. GABAPENTIN 900mg decrease VAS and consumption of analgesic significantly.

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APA: Copy

HASSANI, VALLIOLLAH, IMANI, FARNAD, ALIMIAN, MAHZAD, & ABDOLALIZADE, MASOOME. (2012). COMPARING THE ANALGESIC EFFECT PREGABALIN AND GABAPENTIN AS PREMEDICATION IN LAPAROSCOPIC PROCEDURES. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 2(6), 30-36. SID. https://sid.ir/paper/216378/en

Vancouver: Copy

HASSANI VALLIOLLAH, IMANI FARNAD, ALIMIAN MAHZAD, ABDOLALIZADE MASOOME. COMPARING THE ANALGESIC EFFECT PREGABALIN AND GABAPENTIN AS PREMEDICATION IN LAPAROSCOPIC PROCEDURES. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2012;2(6):30-36. Available from: https://sid.ir/paper/216378/en

IEEE: Copy

VALLIOLLAH HASSANI, FARNAD IMANI, MAHZAD ALIMIAN, and MASOOME ABDOLALIZADE, “COMPARING THE ANALGESIC EFFECT PREGABALIN AND GABAPENTIN AS PREMEDICATION IN LAPAROSCOPIC PROCEDURES,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 2, no. 6, pp. 30–36, 2012, [Online]. Available: https://sid.ir/paper/216378/en

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