COMPARISON OF THE EXPRESSION LEVEL OF P53 AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENES IN THE INFLAMED AND NON-INFLAMED DENTIGEROUS CYSTS

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SEYED MAJIDI M.; KESHMIRI N.; NAFARZADEH S.; BIJANI A.

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Journal: Journal of Kerman University of Medical Sciences Year:2012 | Volume:19 | Issue:6 Page(s): 511-519

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Information Journal Paper

Title

COMPARISON OF THE EXPRESSION LEVEL OF P53 AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENES IN THE INFLAMED AND NON-INFLAMED DENTIGEROUS CYSTS

Author(s)

SEYED MAJIDI M. | KESHMIRI N. | NAFARZADEH S. | BIJANI A. | Issue Writer Certificate

Keywords

P53Q3

PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)Q2

DENTIGEROUS CYSTQ2

INFLAMMATIONQ2

Abstract

Background & Aims: The role of P53 and proliferating cell nuclear antigen (PCNA) genes in inflamed and non-inflamed odontogenic cysts is related to cell proliferation but it is unclear. The aim of this study was immunohistochemical evaluation of P53 and PCNA expression in inflamed and non-inflamed DENTIGEROUS CYSTs.Methods: In the present study, 23 DENTIGEROUS CYSTs (12 inflamed and 11 non-inflamed) were surveyed. Three microns slices were got from paraffined blocks and stained with P53 and PCNA antibodies by immunohistochemistry. Slides were seen by oral pathologist with optical microscope (Olympus BX41) in ×400 magnification and scored by Allred scoring. Data were analyzed by Mann-Whitney test via SPSS software.Results: Percent of stained cells in inflamed compared non-inflamed DENTIGEROUS CYST did not show any significant difference for expression level of P53 and PCNA in basal and suprabasal layers (P>0.05).Conclusion: It seems that INFLAMMATION does not affect on expression level of P53 and PCNA in DENTIGEROUS CYST.

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APA: Copy

SEYED MAJIDI, M., KESHMIRI, N., NAFARZADEH, S., & BIJANI, A.. (2012). COMPARISON OF THE EXPRESSION LEVEL OF P53 AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENES IN THE INFLAMED AND NON-INFLAMED DENTIGEROUS CYSTS. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 19(6), 511-519. SID. https://sid.ir/paper/244/en

Vancouver: Copy

SEYED MAJIDI M., KESHMIRI N., NAFARZADEH S., BIJANI A.. COMPARISON OF THE EXPRESSION LEVEL OF P53 AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENES IN THE INFLAMED AND NON-INFLAMED DENTIGEROUS CYSTS. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;19(6):511-519. Available from: https://sid.ir/paper/244/en

IEEE: Copy

M. SEYED MAJIDI, N. KESHMIRI, S. NAFARZADEH, and A. BIJANI, “COMPARISON OF THE EXPRESSION LEVEL OF P53 AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENES IN THE INFLAMED AND NON-INFLAMED DENTIGEROUS CYSTS,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 19, no. 6, pp. 511–519, 2012, [Online]. Available: https://sid.ir/paper/244/en

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