EVALUATION OF SINGLE DOSE PREGABALIN VS. PLACEBO IN REDUCING POST–PHOTOREFRACTIVE KERATECTOMY PAIN

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CHUBSAZ MANSOUR; DANESHGAR FARID; AMIRI FARD NASRIN; KAZEROONI TAYEBEH; GHADERI EBRAHIM

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Journal: Journal of Clinical Research in Paramedical Sciences Year:2014 | Volume:3 | Issue:3 Page(s): 154-159

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Title

EVALUATION OF SINGLE DOSE PREGABALIN VS. PLACEBO IN REDUCING POST–PHOTOREFRACTIVE KERATECTOMY PAIN

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Keywords

PHOTOREFRACTIVE KERATECTOMYQ2

PREGABALINQ2

PAINQ2

VISUAL ANALOG SCALEQ2

Abstract

Background: Today, PHOTOREFRACTIVE KERATECTOMY (PRK) is one of the most common methods of eye surgery and the most important problem of patient and medical team that are confronted about this surgery is PAIN. The aim of this study was to determine the efficacy of PREGABALIN for reducing post–PHOTOREFRACTIVE KERATECTOMY (PRK) PAIN.Methods: This study was done as a double blind clinical trial. Patients were divided in two groups (40 patients in each group) as case and control and 30 minute before surgery 150 mg PREGABALIN and placebo were prescribed for case and control groups, respectively. In 6, 12 and 24 hours after surgery, PAIN was measured by VISUAL ANALOG SCALE (VAS).Results: The results of this study were showed PAIN score in 6 and 12 hours after surgery in PREGABALIN group was significant lower than control (P<0.001). In PREGABALIN group, after 6 hours, 17 patients (42.5%) had VAS score >3 and needs to Acetaminophen; whereas in control group 33 patients (82.5%) had VAS score >3 (P<0.001). Further, there wasn't any side effect in PREGABALIN group.Conclusion: Our study showed PREGABALIN is an effective and with low side effect medicine for reducing of post–PHOTOREFRACTIVE KERATECTOMY PAIN.

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APA: Copy

CHUBSAZ, MANSOUR, DANESHGAR, FARID, AMIRI FARD, NASRIN, KAZEROONI, TAYEBEH, & GHADERI, EBRAHIM. (2014). EVALUATION OF SINGLE DOSE PREGABALIN VS. PLACEBO IN REDUCING POST–PHOTOREFRACTIVE KERATECTOMY PAIN. JOURNAL OF CLINICAL RESEARCH IN PARAMEDICAL SCIENCES, 3(3), 154-159. SID. https://sid.ir/paper/256081/en

Vancouver: Copy

CHUBSAZ MANSOUR, DANESHGAR FARID, AMIRI FARD NASRIN, KAZEROONI TAYEBEH, GHADERI EBRAHIM. EVALUATION OF SINGLE DOSE PREGABALIN VS. PLACEBO IN REDUCING POST–PHOTOREFRACTIVE KERATECTOMY PAIN. JOURNAL OF CLINICAL RESEARCH IN PARAMEDICAL SCIENCES[Internet]. 2014;3(3):154-159. Available from: https://sid.ir/paper/256081/en

IEEE: Copy

MANSOUR CHUBSAZ, FARID DANESHGAR, NASRIN AMIRI FARD, TAYEBEH KAZEROONI, and EBRAHIM GHADERI, “EVALUATION OF SINGLE DOSE PREGABALIN VS. PLACEBO IN REDUCING POST–PHOTOREFRACTIVE KERATECTOMY PAIN,” JOURNAL OF CLINICAL RESEARCH IN PARAMEDICAL SCIENCES, vol. 3, no. 3, pp. 154–159, 2014, [Online]. Available: https://sid.ir/paper/256081/en

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