PAPILLON LEFEVRE SYNDROME

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LOTF AZAR M.

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Journal Paper

Paper Information

Journal: Journal of Dental Medicine Year:2003 | Volume:15 | Issue:4 (33) Page(s): 68-86

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Information Journal Paper

Title

PAPILLON LEFEVRE SYNDROME

Author(s)

LOTF AZAR M. | Issue Writer Certificate

Keywords

PAPILLON LEFEVRE SYNDROMEQ3

PERIODONTAL DISEASESQ4

CATEPESIN CQ3

ACTINOBACILLOUS CTINOMYCETEMCOMITANSQ4

Abstract

PAPILLON LEFEVRE SYNDROME (PLS) is a rare recessive autosomal disease, which is associated with palm and sole hyperkeratosis and early periodontium break down of deciduouse and permanent dentition. In the differential diagnosis of PLS, congenital form of palm and sole hyperkeratosis should be considered.Recently, mutation in CATEPESIN C gene has been recognized as a genetic basis for PLS disease. In this disease, complete lack of CATEPESIN C enzyme activity, due to the mutations on both allels, are observed. Actinobacillous actinomycetemcomitans (A.a) bacteria are presented as the main periodontal pathogene in PLS disease. The treatment results have been contradictory and no agreement has been obtained in this regard. Elimination of A.a bacteria and administration of synthetic retinoids are reported as a suitable treatment.

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References

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Cite

APA: Copy

LOTF AZAR, M.. (2003). PAPILLON LEFEVRE SYNDROME. JOURNAL OF DENTAL MEDICINE, 15(4 (33)), 68-86. SID. https://sid.ir/paper/25633/en

Vancouver: Copy

LOTF AZAR M.. PAPILLON LEFEVRE SYNDROME. JOURNAL OF DENTAL MEDICINE[Internet]. 2003;15(4 (33)):68-86. Available from: https://sid.ir/paper/25633/en

IEEE: Copy

M. LOTF AZAR, “PAPILLON LEFEVRE SYNDROME,” JOURNAL OF DENTAL MEDICINE, vol. 15, no. 4 (33), pp. 68–86, 2003, [Online]. Available: https://sid.ir/paper/25633/en

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