EVALUATION OF HUMAN LEUKOCYTE ANTIGENS IN PAPILLON LEFEVRE SYNDROME

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LOTF AZAR M.; GHARESIFARD B.; FARGADIAN SH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Dental Medicine Year:2003 | Volume:15 | Issue:4 (33) Page(s): 5-13

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Title

EVALUATION OF HUMAN LEUKOCYTE ANTIGENS IN PAPILLON LEFEVRE SYNDROME

Author(s)

LOTF AZAR M. | GHARESIFARD B. | FARGADIAN SH. | Issue Writer Certificate

Keywords

PREPUBERTAL PERIODONTITISQ4

PAPILLON LEFEVRE SYNDROMEQ3

HLA-B18Q4

Abstract

Papillon Lefevre Syndrome (PLS) is a rare disease, associated with the early onset periodontal break down in deciduous and permanent dentition. The etiology of PLS is not exactly determined but recently, mutation in catespin C gene, as a genetic basis for the disease, has been established. The aim of this study was to investigate the HLA status in patients affected with PLS. In this research, the frequency of HLA-I and HLA-DR in 9 PLS patients (Belonged to seven unrelated families) were compared with 37 healthy people (controls). Fisher exact test was used for data analysis. The results indicated that the frequency of HLA-B18 was significantly higher in the patients’ group, compared to the control group(P<0.05). The present study, based on the serological methods, is the only existing controlled study regarding PLS. However, in order to get accurate results, a molecular technology with more samples is required.

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APA: Copy

LOTF AZAR, M., GHARESIFARD, B., & FARGADIAN, SH.. (2003). EVALUATION OF HUMAN LEUKOCYTE ANTIGENS IN PAPILLON LEFEVRE SYNDROME. JOURNAL OF DENTAL MEDICINE, 15(4 (33)), 5-13. SID. https://sid.ir/paper/25634/en

Vancouver: Copy

LOTF AZAR M., GHARESIFARD B., FARGADIAN SH.. EVALUATION OF HUMAN LEUKOCYTE ANTIGENS IN PAPILLON LEFEVRE SYNDROME. JOURNAL OF DENTAL MEDICINE[Internet]. 2003;15(4 (33)):5-13. Available from: https://sid.ir/paper/25634/en

IEEE: Copy

M. LOTF AZAR, B. GHARESIFARD, and SH. FARGADIAN, “EVALUATION OF HUMAN LEUKOCYTE ANTIGENS IN PAPILLON LEFEVRE SYNDROME,” JOURNAL OF DENTAL MEDICINE, vol. 15, no. 4 (33), pp. 5–13, 2003, [Online]. Available: https://sid.ir/paper/25634/en

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