Evaluation of Prognostic Variables on Time to Relapse In Patients with Hodgkin's Lymphoma Using Classified Cox Model

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Elhaei Amir; SAKI MALEHI AMAL; Seghatoleslami Mohammad

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Journal: DEPICTION OF HEALTH Year:2019 | Volume:10 | Issue:3 Page(s): 227-234

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Title

Evaluation of Prognostic Variables on Time to Relapse In Patients with Hodgkin's Lymphoma Using Classified Cox Model

Author(s)

Elhaei Amir | SAKI MALEHI AMAL | Seghatoleslami Mohammad | Issue Writer Certificate

Keywords

Hodgkin's LymphomaQ3

Survival AnalysisQ3

RelapseQ3

Classified Cox ModelQ3

Abstract

Background and Objectives: Identifying the important influential factors of Relapse in Hodgkin's Lymphoma is a great challenge in oncology studies. Cox regression model is a known method that could be used to evaluate the prognostic factors. This method identifies the main prognostic factors based on Proportional Hazard (PH) assumption. The aim of this study was to evaluate the stratified Cox model and assess the prognostic factors which affected the Relapse time of Hodgkin's Lymphoma in patients hospitalized in Ahvaz Shafa Hospital. Material and Methods: The current study included all the cases of patients who had referred to the research center of oncology and hematology of Shafa hospital in Ahvaz Jundishapure University of medical sciences during 2002-2012. Survival time was considered from date of diagnosis to Relapse (in months) after chemotherapy. Choosing the best model was based on Likelihood Ratio Test. Data analysis was performed using STATA13. Results: The results of the stratified Cox regression model showed that the risk of Relapse is 2 times higher for patients with hemoglobin lower than 10. 5 (P=0. 012). Furthermore, the patients that NLPHL was used as a biopsy method were 96 percent more likely to experience the Relapse compared to CHL biopsy method (P = 0. 155). Conclusion: Using the stratified Cox regression model the hemoglobin less than 10. 5 was identified as a main and significant prognostic factor.

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APA: Copy

Elhaei, Amir, SAKI MALEHI, AMAL, & Seghatoleslami, Mohammad. (2019). Evaluation of Prognostic Variables on Time to Relapse In Patients with Hodgkin's Lymphoma Using Classified Cox Model. DEPICTION OF HEALTH, 10(3 ), 227-234. SID. https://sid.ir/paper/265162/en

Vancouver: Copy

Elhaei Amir, SAKI MALEHI AMAL, Seghatoleslami Mohammad. Evaluation of Prognostic Variables on Time to Relapse In Patients with Hodgkin's Lymphoma Using Classified Cox Model. DEPICTION OF HEALTH[Internet]. 2019;10(3 ):227-234. Available from: https://sid.ir/paper/265162/en

IEEE: Copy

Amir Elhaei, AMAL SAKI MALEHI, and Mohammad Seghatoleslami, “Evaluation of Prognostic Variables on Time to Relapse In Patients with Hodgkin's Lymphoma Using Classified Cox Model,” DEPICTION OF HEALTH, vol. 10, no. 3 , pp. 227–234, 2019, [Online]. Available: https://sid.ir/paper/265162/en

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