HEPATOPROTECTIVE ACTIVITY OF FICUS CARICA LINN. LEAF EXTRACT AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS

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KRISHNA MOHAN G.; PALLAVI E.; RAVI KUMAR B.; RAMESH M.; VENKATESH S.

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Journal Paper

Paper Information

Journal: DARU Journal of Pharmaceutical Sciences Year:2007 | Volume:15 | Issue:3 Page(s): 162-166

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Title

HEPATOPROTECTIVE ACTIVITY OF FICUS CARICA LINN. LEAF EXTRACT AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS

Author(s)

Keywords

FICUS CARICA

LEAVES

HEPATOPROTECTIVE

CARBON TETRACHLORIDE

Abstract

The methanol extract of the LEAVES of FICUS CARICA Linn. (Moraceae) was evaluated for HEPATOPROTECTIVE activity in rats with liver damage induced by CARBON TETRACHLORIDE. The extract at an oral dose of 500 mg/kg exhibited a significant protective effect by lowering the serum levels of aspartate aminotransferase, alanine aminotransferase, total serum bilirubin, and malondialdehyde equivalent, an index of lipid peroxidation of the liver. These biochemical observations were supplemented by histopathological examination of liver sections. The activity of extract was also comparable to that of silymarin, a known HEPATOPROTECTIVE.

Cites

EVALUATION OF THE EFFECT OF ANETHUM GRAVEOLENS L. CRUDE EXTRACTS ONSERUM LIPIDS AND LIPOPROTEINS PROFILES IN HYPERCHOLESTEROLAEMIC RATS

References

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APA: Copy

KRISHNA MOHAN, G., PALLAVI, E., RAVI KUMAR, B., RAMESH, M., & VENKATESH, S.. (2007). HEPATOPROTECTIVE ACTIVITY OF FICUS CARICA LINN. LEAF EXTRACT AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 15(3), 162-166. SID. https://sid.ir/paper/275415/en

Vancouver: Copy

KRISHNA MOHAN G., PALLAVI E., RAVI KUMAR B., RAMESH M., VENKATESH S.. HEPATOPROTECTIVE ACTIVITY OF FICUS CARICA LINN. LEAF EXTRACT AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2007;15(3):162-166. Available from: https://sid.ir/paper/275415/en

IEEE: Copy

G. KRISHNA MOHAN, E. PALLAVI, B. RAVI KUMAR, M. RAMESH, and S. VENKATESH, “HEPATOPROTECTIVE ACTIVITY OF FICUS CARICA LINN. LEAF EXTRACT AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 15, no. 3, pp. 162–166, 2007, [Online]. Available: https://sid.ir/paper/275415/en

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