THE EFFECT OF L-CARNITINE AND 10 WEEKS OF AEROBIC EXERCISE ON SERUM LEVELS OF CRP IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JALILI M.; HEIDARIANPOUR A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Endocrinology & Metabolism Year:2016 | Volume:17 | Issue:6 Page(s): 435-439

Download Full-Text

Persian Verion

View:

858

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF L-CARNITINE AND 10 WEEKS OF AEROBIC EXERCISE ON SERUM LEVELS OF CRP IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Author(s)

JALILI M. | HEIDARIANPOUR A. | Issue Writer Certificate

Keywords

TYPE 1 DIABETES MELLITUSQ2

CARDIOVASCULAR COMPLICATIONSQ2

CRPQ2

AEROBIC TRAININGQ2

L-CARNITINEQ2

Abstract

Introduction: CARDIOVASCULAR COMPLICATIONS are considered as the main cause of morbidity and mortality in patients with diabetes mellitus. The role of increased serum concentrations of inflammatory markers, particularly C Reactive Protein (CRP), in the prediction and the pathogenesis of CARDIOVASCULAR COMPLICATIONS of type 1 diabetes has been established. The aim of the present study was to evaluate the effect of 10 weeks of L-CARNITINE supplementation and aerobic exercise training on serum levels of CRP in streptozotocin-induced diabetic rats. Materials and Methods: Male wistar rats (n=36), weighing 230±10 (grams) were randomly divided into 6 groups (n=6 each), including the healthy group, and the remaining (after the induction of diabetes mellitus by injection of streptozotocin), into the diabetic pre-test, diabetic control, diabetic AEROBIC TRAINING, diabetic oral L-CARNITINE treatment, and the diabetic AEROBIC TRAINING plus oral L-CARNITINE treatment groups. At the end of the interventions, blood samples were collected to determine serum levels of CRP. Data were analyzed with one-way ANOVA and Tukey's post hoc test using SPSS version 20; P values<0.05 were considered significant.Results: Althought L-CARNITINE supplementation in diabetic oral L-CARNITINE treatment group did not significantly reduce serum levels of CRP, compared with the diabetic control group (p=0.078), it however reduced the rate of its progressive increase. Also significant reductions in CRP levels in both the AEROBIC TRAINING (p=0.00021) and the AEROBIC TRAINING plus L-CARNITINE supplementation groups (p<0.0001) were observed. However, the percentage changes of CRP level in the latter group was higher.Conclusion: Results of the current study show that, AEROBIC TRAINING can reduce serum CRP levels in streptozotocin-induced diabetic rats, and the simultaneous use of L-CARNITINE supplementation, can lead to more beneficial effects.

Cites

No record.

References

No record.

Cite

APA: Copy

JALILI, M., & HEIDARIANPOUR, A.. (2016). THE EFFECT OF L-CARNITINE AND 10 WEEKS OF AEROBIC EXERCISE ON SERUM LEVELS OF CRP IN STREPTOZOTOCIN-INDUCED DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 17(6), 435-439. SID. https://sid.ir/paper/27720/en

Vancouver: Copy

JALILI M., HEIDARIANPOUR A.. THE EFFECT OF L-CARNITINE AND 10 WEEKS OF AEROBIC EXERCISE ON SERUM LEVELS OF CRP IN STREPTOZOTOCIN-INDUCED DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2016;17(6):435-439. Available from: https://sid.ir/paper/27720/en

IEEE: Copy

M. JALILI, and A. HEIDARIANPOUR, “THE EFFECT OF L-CARNITINE AND 10 WEEKS OF AEROBIC EXERCISE ON SERUM LEVELS OF CRP IN STREPTOZOTOCIN-INDUCED DIABETIC RATS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 17, no. 6, pp. 435–439, 2016, [Online]. Available: https://sid.ir/paper/27720/en

Related Journal Papers