مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

456
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

119
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

2

Information Journal Paper

Title

TRANSFORMING GROWTH FACTOR BETA-INDUCED FACTOR 2-LINKED X (TGIF2LX) REGULATES TWO MORPHOGENESIS GENES, NIR1 AND NIR2 IN HUMAN COLORECTAL

Pages

  302-307

Abstract

 A member of homeodomain protein namely TGIF2LX has been implicated as a TUMOR SUPPRESSOR gene in human malignancy as well as in spermatogenesis. However, to our knowledge, dynamic functional evidence of the TGIF2LX has not yet been provided. The aim of the present study was to investigate the human TGIF2LX target gene (s) using a CDNA-AFLP as a differential display method. A pEGFP-TGIF2LX construct containing the wild-type TGIF2LX cDNA was stably transfected into SW48 cells. UV microscopic analysis and Real-time RT-PCR were used to confirm TGIF2LX expression. The mRNA expressions of TGIF2LX in transfected SW48 cells, the cells containing empty vector (pEGFP-N), and untransfected cells were compared. Also, a Real-time PCR technique was applied to validate CDNA-AFLP results. The results revealed a significant down-regulation and up-regulationby TGIF2LX of Nir1 and Nir2 genes, respectively.The genes are engaged in the cell morphogenesis process. Our findings may provide new insight into the complex molecular pathways underlying COLORECTAL CANCER development.

Cites

References

Cite

APA: Copy

MOBINI, GHOLAMREZA, GHAHREMANI, MOHAMMAD HOSSEIN, AMANPOUR, SAEID, DEHPOUR, AHMAD REZA, AKBARI, ABOLFAZL, HOSEINI HAROUNI, SEYED MOJTABA, MUHAMMADNEJAD, SAMAD, SHEIKHZADE, MARYAM, ABEDKHOJASTEH, HODA, MOHEBI, MASOUMEH, BOLHASSANI, MANZAR, & HEIDARI, MANSOUR. (2016). TRANSFORMING GROWTH FACTOR BETA-INDUCED FACTOR 2-LINKED X (TGIF2LX) REGULATES TWO MORPHOGENESIS GENES, NIR1 AND NIR2 IN HUMAN COLORECTAL. ACTA MEDICA IRANICA, 54(5), 302-307. SID. https://sid.ir/paper/278836/en

Vancouver: Copy

MOBINI GHOLAMREZA, GHAHREMANI MOHAMMAD HOSSEIN, AMANPOUR SAEID, DEHPOUR AHMAD REZA, AKBARI ABOLFAZL, HOSEINI HAROUNI SEYED MOJTABA, MUHAMMADNEJAD SAMAD, SHEIKHZADE MARYAM, ABEDKHOJASTEH HODA, MOHEBI MASOUMEH, BOLHASSANI MANZAR, HEIDARI MANSOUR. TRANSFORMING GROWTH FACTOR BETA-INDUCED FACTOR 2-LINKED X (TGIF2LX) REGULATES TWO MORPHOGENESIS GENES, NIR1 AND NIR2 IN HUMAN COLORECTAL. ACTA MEDICA IRANICA[Internet]. 2016;54(5):302-307. Available from: https://sid.ir/paper/278836/en

IEEE: Copy

GHOLAMREZA MOBINI, MOHAMMAD HOSSEIN GHAHREMANI, SAEID AMANPOUR, AHMAD REZA DEHPOUR, ABOLFAZL AKBARI, SEYED MOJTABA HOSEINI HAROUNI, SAMAD MUHAMMADNEJAD, MARYAM SHEIKHZADE, HODA ABEDKHOJASTEH, MASOUMEH MOHEBI, MANZAR BOLHASSANI, and MANSOUR HEIDARI, “TRANSFORMING GROWTH FACTOR BETA-INDUCED FACTOR 2-LINKED X (TGIF2LX) REGULATES TWO MORPHOGENESIS GENES, NIR1 AND NIR2 IN HUMAN COLORECTAL,” ACTA MEDICA IRANICA, vol. 54, no. 5, pp. 302–307, 2016, [Online]. Available: https://sid.ir/paper/278836/en

Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button