OPIUM AS A RISK FACTOR FOR BLADDER CANCER: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN

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AKBARI MORTEZA; NAGHIBZADEH TAHAMI AHMAD; KHANJANI NARGES; BANESHI MOHAMMAD REZA; KAMALI ELHAM; HESAMPOUR MARYAM; NAZEMZADEGAN BAHMAN; HAGHDOOST ALI AKBAR

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2015 | Volume:18 | Issue:9 Page(s): 567-571

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Title

OPIUM AS A RISK FACTOR FOR BLADDER CANCER: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN

Author(s)

Keywords

BLADDER NEOPLASMS

CASE-CONTROL

IRAN

OPIUM

RISK FACTOR

Abstract

BACKGROUND: Bladder cancer (BC) is the most common genitourinary system malignancy in humans. Consumption of opium and its derivatives, maybe a risk factor possibly in Iran. The aim of this study was to investigate the relationship between consumption of opium and its derivatives and the incidence of BC.METHODS: In an individually matched case-control study in Shiraz (located in the south of Iran), 198 patients with BC and 396 healthy individuals (matched in age, sex and residence (urban/rural)) were investigated. Data about consumption of opium and its derivatives, tobacco, alcohol and diet were collected using a structured valid and reliable questionnaire. Crude and adjusted odds ratios (ORs) were computed using conditional logistic regression models.RESULTS: Opium consumption was associated with an increased risk of BC with an adjusted OR = 3.9 (95% CI: 1.2 – 12.0). Moreover, a considerable dose-response relationship was observed between the opium consumption and its derivatives and the incidence of BC; comparing to no users, the odds ratios of low and high consumptions were 3.3 (95% CI: 0.5 – 23.1) and 4.9 (95% CI: 1.1 – 21.9) respectively.CONCLUSION: Opium consumption can be a potential strong risk factor for BC in Iran.

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APA: Copy

AKBARI, MORTEZA, NAGHIBZADEH TAHAMI, AHMAD, KHANJANI, NARGES, BANESHI, MOHAMMAD REZA, KAMALI, ELHAM, HESAMPOUR, MARYAM, NAZEMZADEGAN, BAHMAN, & HAGHDOOST, ALI AKBAR. (2015). OPIUM AS A RISK FACTOR FOR BLADDER CANCER: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN. ARCHIVES OF IRANIAN MEDICINE, 18(9), 567-571. SID. https://sid.ir/paper/281287/en

Vancouver: Copy

AKBARI MORTEZA, NAGHIBZADEH TAHAMI AHMAD, KHANJANI NARGES, BANESHI MOHAMMAD REZA, KAMALI ELHAM, HESAMPOUR MARYAM, NAZEMZADEGAN BAHMAN, HAGHDOOST ALI AKBAR. OPIUM AS A RISK FACTOR FOR BLADDER CANCER: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2015;18(9):567-571. Available from: https://sid.ir/paper/281287/en

IEEE: Copy

MORTEZA AKBARI, AHMAD NAGHIBZADEH TAHAMI, NARGES KHANJANI, MOHAMMAD REZA BANESHI, ELHAM KAMALI, MARYAM HESAMPOUR, BAHMAN NAZEMZADEGAN, and ALI AKBAR HAGHDOOST, “OPIUM AS A RISK FACTOR FOR BLADDER CANCER: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN,” ARCHIVES OF IRANIAN MEDICINE, vol. 18, no. 9, pp. 567–571, 2015, [Online]. Available: https://sid.ir/paper/281287/en

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