CLINICAL SIGNIFICANT OF PERICENTRIC OF CHROMOSOME 9:A REPORT OF RECURRENT ABORTION

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AREFI S.S.; MODDARESSI M.H.; JEDI TEHRANI MAHMOUD; AZIZI F.

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Journal: Journal of Reproduction & Infertility Year:2003 | Volume:4 | Issue:3 (15) Page(s): 251-258

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Title

CLINICAL SIGNIFICANT OF PERICENTRIC OF CHROMOSOME 9:A REPORT OF RECURRENT ABORTION

Author(s)

AREFI S.S. | MODDARESSI M.H. | JEDI TEHRANI MAHMOUD | AZIZI F. | Issue Writer Certificate

Keywords

RECURRENT ABORTIONQ3

INVERSION OF CHROMOSOME 9Q3

INTRAUTERINE FETAL DEATH (IUFD)Q3

AND INFERTILITYQ3

Abstract

Pericentric INVERSION OF CHROMOSOME 9 is a common phenomenon which is considered as normal variant by some cytogeneticists. A phenotipically normal couple was referred for cytogenetic evaluation due to ten recurrent spontaneous abortions and one intrauterine fetal death. The history of infertility, RECURRENT ABORTION and intrauterine fetal death were seen in the family and in the first and second degree relatives of the female. Chromosomal analysis from peripheral blood was performed according to standard cytogenetic methods using G-banding and C-banding techniques. Husbands karyotype was normal. Wife's karyotype has shown pericentric INVERSION OF CHROMOSOME 9, inv (9) (pll-q13). Culture of peripheral blood, umbilical cord, chorionic villi and muscle biopsy were done on the last aborted fetus. Chromosomal study of the fetus revealed 46XY without any significant problem except for elongation of centromeric region of chromosome 9.It seems that pericentric INVERSION OF CHROMOSOME 9 is frequently observed in individuals with RECURRENT ABORTION, intrauterine fetal death, stillbirth, but as the etiology, the clinical significance is still uncertain we discuss this issue in our report.

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APA: Copy

AREFI, S.S., MODDARESSI, M.H., JEDI TEHRANI, MAHMOUD, & AZIZI, F.. (2003). CLINICAL SIGNIFICANT OF PERICENTRIC OF CHROMOSOME 9:A REPORT OF RECURRENT ABORTION. JOURNAL OF REPRODUCTION AND INFERTILITY, 4(3 (15)), 251-258. SID. https://sid.ir/paper/28281/en

Vancouver: Copy

AREFI S.S., MODDARESSI M.H., JEDI TEHRANI MAHMOUD, AZIZI F.. CLINICAL SIGNIFICANT OF PERICENTRIC OF CHROMOSOME 9:A REPORT OF RECURRENT ABORTION. JOURNAL OF REPRODUCTION AND INFERTILITY[Internet]. 2003;4(3 (15)):251-258. Available from: https://sid.ir/paper/28281/en

IEEE: Copy

S.S. AREFI, M.H. MODDARESSI, MAHMOUD JEDI TEHRANI, and F. AZIZI, “CLINICAL SIGNIFICANT OF PERICENTRIC OF CHROMOSOME 9:A REPORT OF RECURRENT ABORTION,” JOURNAL OF REPRODUCTION AND INFERTILITY, vol. 4, no. 3 (15), pp. 251–258, 2003, [Online]. Available: https://sid.ir/paper/28281/en

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