SERUM HOMOCYSTEINE LEVELS IN PCOS PATIENTS VERSUS HEALTHY WOMEN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOHRABVAND F.; LANKARANI M.; GOLESTAN B.; HAGH ELAHI F.; ASGARPOUR L.; BADAMCHIZADEH Z.; MASOUMI MASOUMEH; JAVADI EBRAHIM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Reproduction & Infertility Year:2009 | Volume:9 | Issue:4 (37) Page(s): 334-341

Download Full-Text

Persian Verion

View:

1,736

Download:

Cites:

Information Journal Paper

Title

SERUM HOMOCYSTEINE LEVELS IN PCOS PATIENTS VERSUS HEALTHY WOMEN

Author(s)

Keywords

FEMALE INFERTILITYQ2

FOLIC ACIDQ3

HOMOCYSTEINEQ2

POLYCYSTIC OVARY SYNDROME (PCOS)Q1

Abstract

Introduction: Patients with PCOS have risk factors for cardiovascular diseases, especially elevated lipoproteins, high blood pressure or hyperinsulinaemia. Clinical evidence shows that hyperhomocysteinaemia may contribute to the development of cardiovascular diseases in PCOS patients. In this study we compared serum HOMOCYSTEINE levels in PCOS patients with healthy Iranian women.Materials and Methods: This case-control study was performed on 52 individuals with PCOS (Rotterdam 2003 criteria). The cases were compared to 104 healthy non-PCOS, 20 to 35-year-old female subjects with no history of diabetes or renal diseases. The cases had referred to the Gynecology and Infertility Clinic of Vali-e-Asr Hospital in Tehran. Blood samples were taken on the 2nd to the 5th day of menstrual cycle for the evaluation of HOMOCYSTEINE levels, FOLIC ACID, triglyceride, insulin and some other metabolic and endocrine parameters. Results: Serum levels of insulin and folate were significantly higher in PCOS patients (16.62±7.45mIU/ml and 7.48±4.37ng/ml) compared to the controls (12.04±4.23mIU/ml and 5.43±3.15ng/ml), (p<0.001). Serum triglyceride concentrations were significantly higher in PCOS patients (116.62±73.02mg/dl) compared to the healthy subjects (88.00±50.29mg/dl), (p=0.01). The mean value for HOMOCYSTEINE (±SD) was 12.21 (±4.55) and 13.68 (±4.37) mmol/L in PCOS and healthy women, respectively but no significant statistical differences were observed (p=0.057). Regression analyses depicted that HOMOCYSTEINE level was mostly under the influence of folate and FBS concentrations.Conclusion: There is an inverse correlation between HOMOCYSTEINE and serum FOLIC ACID levels in PCOS patients. Therefore, it seems that proper administration of FOLIC ACID can reduce HOMOCYSTEINE levels in patients with PCOS and help prevent the attributed cardiovascular risk factors associated with the disease.

Cites

EVALUATION OF THROMBOPHILIC FACTORS IN WOMEN WITH PCOS

References

No record.

Cite

APA: Copy

SOHRABVAND, F., LANKARANI, M., GOLESTAN, B., HAGH ELAHI, F., ASGARPOUR, L., BADAMCHIZADEH, Z., MASOUMI, MASOUMEH, & JAVADI, EBRAHIM. (2009). SERUM HOMOCYSTEINE LEVELS IN PCOS PATIENTS VERSUS HEALTHY WOMEN. JOURNAL OF REPRODUCTION AND INFERTILITY, 9(4 (37)), 334-341. SID. https://sid.ir/paper/28324/en

Vancouver: Copy

SOHRABVAND F., LANKARANI M., GOLESTAN B., HAGH ELAHI F., ASGARPOUR L., BADAMCHIZADEH Z., MASOUMI MASOUMEH, JAVADI EBRAHIM. SERUM HOMOCYSTEINE LEVELS IN PCOS PATIENTS VERSUS HEALTHY WOMEN. JOURNAL OF REPRODUCTION AND INFERTILITY[Internet]. 2009;9(4 (37)):334-341. Available from: https://sid.ir/paper/28324/en

IEEE: Copy

F. SOHRABVAND, M. LANKARANI, B. GOLESTAN, F. HAGH ELAHI, L. ASGARPOUR, Z. BADAMCHIZADEH, MASOUMEH MASOUMI, and EBRAHIM JAVADI, “SERUM HOMOCYSTEINE LEVELS IN PCOS PATIENTS VERSUS HEALTHY WOMEN,” JOURNAL OF REPRODUCTION AND INFERTILITY, vol. 9, no. 4 (37), pp. 334–341, 2009, [Online]. Available: https://sid.ir/paper/28324/en

Related Journal Papers