HLA-G5 AND G7 ISOFORMS IN PREGNANT WOMEN (BRIEF COMMUNICATION)

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ABEDIANKENARI SAEID; FARZAD FARAMARS; RAHMANI ZAHRA; HASHEMI SOTEH MOHAMMAD BAGHER

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Journal Paper

Paper Information

Journal: Iranian Journal of Allergy, Asthma and Immunology Year:2015 | Volume:14 | Issue:2 Page(s): 217-221

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Information Journal Paper

Title

HLA-G5 AND G7 ISOFORMS IN PREGNANT WOMEN (BRIEF COMMUNICATION)

Author(s)

ABEDIANKENARI SAEID | FARZAD FARAMARS | RAHMANI ZAHRA | HASHEMI SOTEH MOHAMMAD BAGHER | Issue Writer Certificate

Keywords

ABORTION

HLA-G

PREGNANCY

Abstract

Human leukocyte antigen-G which is an immune tolerance effecter molecule has an important role in the maintenance of fetus during PREGNANCY. ABORTION is one of the complications of PREGNANCY period. In this research, we have studied levels of HLA-G 5, HLA-G7 isoforms in the ABORTION-threatened pregnant women in comparison with controls.In a case-control study, 101 ABORTION-threatened women and 101 healthy pregnant women (healthy controls) with age range 21-32 years were studied. Gene expression of HLA-5 and HLA-7 isoforms was analyzed by real-time polymerase chain reaction after mRNA extraction and cDNA synthesis.The results indicated that HLA-G5 was significantly lower in ABORTION-threatened women in comparison with the control group whereas HLA-G7 was not significantly different between the 2 groups.HLA-G is a vital molecule during PREGNANCY that can be a key factor in prevention of ABORTION. It is concluded that determination of HLA-G5 can be of value in PREGNANCY.

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APA: Copy

ABEDIANKENARI, SAEID, FARZAD, FARAMARS, RAHMANI, ZAHRA, & HASHEMI SOTEH, MOHAMMAD BAGHER. (2015). HLA-G5 AND G7 ISOFORMS IN PREGNANT WOMEN (BRIEF COMMUNICATION). IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 14(2), 217-221. SID. https://sid.ir/paper/291430/en

Vancouver: Copy

ABEDIANKENARI SAEID, FARZAD FARAMARS, RAHMANI ZAHRA, HASHEMI SOTEH MOHAMMAD BAGHER. HLA-G5 AND G7 ISOFORMS IN PREGNANT WOMEN (BRIEF COMMUNICATION). IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2015;14(2):217-221. Available from: https://sid.ir/paper/291430/en

IEEE: Copy

SAEID ABEDIANKENARI, FARAMARS FARZAD, ZAHRA RAHMANI, and MOHAMMAD BAGHER HASHEMI SOTEH, “HLA-G5 AND G7 ISOFORMS IN PREGNANT WOMEN (BRIEF COMMUNICATION),” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 14, no. 2, pp. 217–221, 2015, [Online]. Available: https://sid.ir/paper/291430/en

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