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Title

EFFECT OF FRESH ROYAL JELLY INGESTION ON GLYCEMIC RESPONSE IN PATIENTS WITH TYPE 2 DIABETES

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Abstract

 Background: Type 2 diabetes is the fourth major public health problem worldwide. ROYAL JELLY (RJ) insulin-like activity and blood glucose modulating properties have been reported in animal and healthy volunteers.Objectives: This study aimed to investigate the effect of a single dose of fresh RJ as a complementary therapy on glycemic response in patients with type 2 diabetes.Patients and Methods: In this randomized clinical trial, 40 patients with type 2 diabetes were assigned into the RJ (n=20) and placebo (n=20) groups and received either 10 g fresh RJ or placebo after overnight fasting. Serum glucose, insulin and C-peptide concentrations were determined at 0, 60, 120 minutes after the intervention. Independent t-tests and repeated measures ANOVA were used to analyze data.Results: The mean serum glucose levels were significantly decreased in RJ and placebo groups; however, mean serum level was different but not statistically. (P=0.77). One hour after RJ ingestion the mean serum insulin concentrations were increased and after 2 hours it was decreased insignificantly (P=0.54, P=0.20). The mean C-peptide concentrations were significantly increased after 1 and 2 hours of RJ ingestion; however, in the placebo group we observed a slight but insignificant reduction at the time of 1 and 2 hours in the mean C-peptide serum levels (P=0.40). Moreover, there was no significant difference in none of the GLYCEMIC CONTROL parameters between both studied groups (P>0.05).Conclusions: It seems that RJ does not appear to have significant immediate effects on glycemic factors in patients with type 2 diabetes. However, further studies with larger sample sizes and different doses of RJ are needed to achieve more precise results.

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APA: Copy

MOBASSERI, MAJID, GHIYASVAND, SHAHRAM, OSTADRAHIMI, ALIREZA, GHOJAZADEH, MORTEZA, NOSHAD, HAMID, & POURMORADIAN, SAMIRA. (2015). EFFECT OF FRESH ROYAL JELLY INGESTION ON GLYCEMIC RESPONSE IN PATIENTS WITH TYPE 2 DIABETES. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 17(9), 0-0. SID. https://sid.ir/paper/293173/en

Vancouver: Copy

MOBASSERI MAJID, GHIYASVAND SHAHRAM, OSTADRAHIMI ALIREZA, GHOJAZADEH MORTEZA, NOSHAD HAMID, POURMORADIAN SAMIRA. EFFECT OF FRESH ROYAL JELLY INGESTION ON GLYCEMIC RESPONSE IN PATIENTS WITH TYPE 2 DIABETES. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2015;17(9):0-0. Available from: https://sid.ir/paper/293173/en

IEEE: Copy

MAJID MOBASSERI, SHAHRAM GHIYASVAND, ALIREZA OSTADRAHIMI, MORTEZA GHOJAZADEH, HAMID NOSHAD, and SAMIRA POURMORADIAN, “EFFECT OF FRESH ROYAL JELLY INGESTION ON GLYCEMIC RESPONSE IN PATIENTS WITH TYPE 2 DIABETES,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 17, no. 9, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/293173/en

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