ORAL MORPHINE CONSUMPTION INHIBITS PLACENTAL DEVELOPMENT IN NINE DAY PREGNANT WISTAR RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KAZEMI M.; AZARNIA MAHNAZ; SAHRAEI HEDAYAT

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE Year:2009 | Volume:7 | Issue:SUPPL 1 Page(s): 0-0

Download Full-Text

View:

252

Download:

Cites:

Information Journal Paper

Title

ORAL MORPHINE CONSUMPTION INHIBITS PLACENTAL DEVELOPMENT IN NINE DAY PREGNANT WISTAR RATS

Author(s)

KAZEMI M. | AZARNIA MAHNAZ | SAHRAEI HEDAYAT

Keywords

PLACENTA

MATERNAL PORTION

FETAL PORTION

LACUNA

MORPHINE

RAT

Abstract

Introduction: Previous studies indicated that morphine consumption during pregnancy could inhibit embryo development. Present study further evaluated the effects of oral morphine consumption on the placental development in nine days pregnant rats.Materials and Methods: Female Wistar rats (170- 200 g) were used in the present study. Experimental group received morphine (0.05 mg/ml of tap water) one night after mating with male rats. On the 9th day of pregnancy, the pregnant animals were anesthetized with chloroform and the placentas were removed surgically and fixed in 10% formalin. The fixed placentas were processed and stained by H and E method and evaluated for their development. Thickness of layers, number and surface area of lacuna, as well as number of the cells in both maternal and fetal parts of the placentas and the utrian septum thickness were calculated by MOTIC software.Results: Our results indicated that both maternal and fetal layer thickness were increased in experimental group. In addition, number and surface area of lacuna, as well as number of the cells in both maternal and fetal parts of the placentas were increased in experimental group. In contrast, the utrine septum thickness was reduced in experimental group.Conclusion: Taken together, our results showed that all placental development indicators were abnormal in experimental group. These abnormalities may be the cause of incomplete development observed in the fetus born by opioid addicted women.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

KAZEMI, M., AZARNIA, MAHNAZ, & SAHRAEI, HEDAYAT. (2009). ORAL MORPHINE CONSUMPTION INHIBITS PLACENTAL DEVELOPMENT IN NINE DAY PREGNANT WISTAR RATS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 7(SUPPL 1), 0-0. SID. https://sid.ir/paper/295222/en

Vancouver: Copy

KAZEMI M., AZARNIA MAHNAZ, SAHRAEI HEDAYAT. ORAL MORPHINE CONSUMPTION INHIBITS PLACENTAL DEVELOPMENT IN NINE DAY PREGNANT WISTAR RATS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2009;7(SUPPL 1):0-0. Available from: https://sid.ir/paper/295222/en

IEEE: Copy

M. KAZEMI, MAHNAZ AZARNIA, and HEDAYAT SAHRAEI, “ORAL MORPHINE CONSUMPTION INHIBITS PLACENTAL DEVELOPMENT IN NINE DAY PREGNANT WISTAR RATS,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 7, no. SUPPL 1, pp. 0–0, 2009, [Online]. Available: https://sid.ir/paper/295222/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops