EFFECT OF HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE 1 (HTLV-1) IN SEROPOSITIVE INFERTILE WOMEN ON INTRACYTOPLASMIC SPERM INJECTION (ICSI) OUTCOME

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MANSOURI TORSHIZI MAHNAZ; KHALIGHI AMIR REZA; FADAVI ISLAM MAHLA; ARAM RAHELE; SABOURI ELHAM; KHALILIFAR HEKMAT; ROUSTAEE HESAM

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Journal: International Journal of Reproductive BioMedicine Year:2014 | Volume:12 | Issue:1 Page(s): 15-18

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Title

EFFECT OF HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE 1 (HTLV-1) IN SEROPOSITIVE INFERTILE WOMEN ON INTRACYTOPLASMIC SPERM INJECTION (ICSI) OUTCOME

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Keywords

HTLV-1

ICSI OUTCOME

SEROPOSITIVE

INFERTILE

Abstract

Background: Human T-cell Lymphotrophic virus type 1 (HTLV-1) has infected more than 20 million people worldwide. Northeast of Iran, Mashhad, the capital of Razavi Khorasan Province, is endemic for HTLV-1 with a prevalence of 3% among general population.Objective: We evaluated the ICSI OUTCOME in our program for (HTLV-1) serodiscordant couples (SDCs) with the female infected in comparison with control group.Materials and Methods: This study was performed between 2007 and 2011 in Novin Infertility Treatment Center (Mashhad, Iran). We examined 32 ICSI cycles of HTLV-1 infected women in comparison with an age matched control group (n=62). ICSI OUTCOME was compared regarding fertilization rate (FR), embryo quality parameters, implantation rate (IR), clinical pregnancy rate (PR), and abortion rate (AR).Results: Fertilization (p=0.15), implantation (p=0.33), and pregnancy rate (p=0.12) were similar between the groups. No difference was found regarding the number of transferred embryos (on day 2 or 3) and cryopreserved embryos, multiple pregnancies, or abortion rates between the groups.Conclusion: Our results suggest that the embryo quality and ICSI OUTCOME are not affected by HTLV-1 infection in serodiscordant couples. The major finding of this study is that the outcome of ICSI in HIV-I-infected patients and seronegative controls is similar.

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APA: Copy

MANSOURI TORSHIZI, MAHNAZ, KHALIGHI, AMIR REZA, FADAVI ISLAM, MAHLA, ARAM, RAHELE, SABOURI, ELHAM, KHALILIFAR, HEKMAT, & ROUSTAEE, HESAM. (2014). EFFECT OF HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE 1 (HTLV-1) IN SEROPOSITIVE INFERTILE WOMEN ON INTRACYTOPLASMIC SPERM INJECTION (ICSI) OUTCOME. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 12(1), 15-18. SID. https://sid.ir/paper/296054/en

Vancouver: Copy

MANSOURI TORSHIZI MAHNAZ, KHALIGHI AMIR REZA, FADAVI ISLAM MAHLA, ARAM RAHELE, SABOURI ELHAM, KHALILIFAR HEKMAT, ROUSTAEE HESAM. EFFECT OF HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE 1 (HTLV-1) IN SEROPOSITIVE INFERTILE WOMEN ON INTRACYTOPLASMIC SPERM INJECTION (ICSI) OUTCOME. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2014;12(1):15-18. Available from: https://sid.ir/paper/296054/en

IEEE: Copy

MAHNAZ MANSOURI TORSHIZI, AMIR REZA KHALIGHI, MAHLA FADAVI ISLAM, RAHELE ARAM, ELHAM SABOURI, HEKMAT KHALILIFAR, and HESAM ROUSTAEE, “EFFECT OF HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE 1 (HTLV-1) IN SEROPOSITIVE INFERTILE WOMEN ON INTRACYTOPLASMIC SPERM INJECTION (ICSI) OUTCOME,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 12, no. 1, pp. 15–18, 2014, [Online]. Available: https://sid.ir/paper/296054/en

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