The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An experimental study

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Fani Masoumeh; MOHAMMADIPOUR ABBAS; EBRAHIMZADEH BIDESKAN ALIREZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2018 | Volume:16 | Issue:8 Page(s): 519-528

Download Full-Text

View:

314

Download:

150

Cites:

Information Journal Paper

Title

The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An experimental study

Author(s)

Fani Masoumeh | MOHAMMADIPOUR ABBAS | EBRAHIMZADEH BIDESKAN ALIREZA | Issue Writer Certificate

Keywords

Atrazine

Crocin

Apoptosis

Spermatogenesis

Mouse

Abstract

Background: Atrazine as a herbicide may affect the human’ s health. Crocin may protect Atrazine-induced damages. Objective: The aim of this study was to evaluate the effects of Atrazine on mice testicular tissue and sperm parameters and protective effects of Crocin on probably Atrazine-induced damages. Materials and Methods: in this experimental study, 24 pregnant Balb/c mice were randomly divided to 4 groups: I: Atrazine (10 mg/kg), II: Atrazine-Crocin, III: Crocin (10mg/kg) and IV: Normal saline. Administrations were done daily by gavage during pregnancy and lactation. In the end, two male offspring were randomly selected from every mother and sacrificed respectively on 23 and 75 postnatal days. Then, their epididymides were removed for sperm parameters investigation and their testes were prepared to evaluate Apoptosis by means of TUNEL technique. Results: The mean number of sperms in the Atrazine group was lower compared to other groups and increased in the Atrazine-Crocin group compared with Atrazine group significantly (p=0. 001). Sperm abnormality was increased in the Atrazine group compared with the normal saline group and decreased in the Atrazine-Crocin group compared with Atrazine group significantly (p≤ 0. 001). TUNEL-positive spermatogonia in 23 days old offspring increased significantly in the Atrazine group compared with other groups (p=0. 03). TUNEL-positive spermatogenic cells in 75 days old offspring was significantly increased in the Atrazine group compared with the saline group (p≤ 0. 001). Conclusion: Atrazine exposure may lead to decrease the number of sperms, increase sperms abnormality, spermatogenic cell Apoptosis and height of germinal epithelium. These complications may improve by Crocin administration.

Cites

No record.

References

Cite

APA: Copy

Fani, Masoumeh, MOHAMMADIPOUR, ABBAS, & EBRAHIMZADEH BIDESKAN, ALIREZA. (2018). The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An experimental study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 16(8), 519-528. SID. https://sid.ir/paper/296539/en

Vancouver: Copy

Fani Masoumeh, MOHAMMADIPOUR ABBAS, EBRAHIMZADEH BIDESKAN ALIREZA. The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An experimental study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2018;16(8):519-528. Available from: https://sid.ir/paper/296539/en

IEEE: Copy

Masoumeh Fani, ABBAS MOHAMMADIPOUR, and ALIREZA EBRAHIMZADEH BIDESKAN, “The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An experimental study,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 16, no. 8, pp. 519–528, 2018, [Online]. Available: https://sid.ir/paper/296539/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops