HCG, THE CENTERPIECE OF LIFE AND DEATH

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COLE LAURENCE A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM Year:2011 | Volume:9 | Issue:2 Page(s): 335-352

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Information Journal Paper

Title

HCG, THE CENTERPIECE OF LIFE AND DEATH

Author(s)

COLE LAURENCE A. | Issue Writer Certificate

Keywords

HUMAN CHORIONIC GONADOTROPIN

CYTOTROPHOBLAST

CHORIOCARCINOMA

Abstract

hCG is a generic name for 5 biologically active molecules that share a common a and b subunit amino acid sequence. These 5 molecules have key biological function in human pregnancy and human cancer. This review examines these molecule in detail. These 5 molecules, hCG, sulfated hCG, hyper glycosylated hCG, hCG free s and hyper glycosylated free s are produced by placental syncytiotrophoblast cells and pituitary gonadotrope cells (group 1), and by placental cytotrophoblast cells and human malignancies (group 2). Group 1 molecules are both hormones that act on the hCG/LH receptor. These molecules are central to human menstrual cycle and human pregnancy. Group 2 molecules are autocrines that act by antagonizing a TGFs receptor. These molecules are critical to all advanced malignancies.The hCG groups are molecules critical to both the molecules of pregnancy or human life, and to the advancement of cancer, or human death.

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APA: Copy

COLE, LAURENCE A.. (2011). HCG, THE CENTERPIECE OF LIFE AND DEATH. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 9(2), 335-352. SID. https://sid.ir/paper/297486/en

Vancouver: Copy

COLE LAURENCE A.. HCG, THE CENTERPIECE OF LIFE AND DEATH. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2011;9(2):335-352. Available from: https://sid.ir/paper/297486/en

IEEE: Copy

LAURENCE A. COLE, “HCG, THE CENTERPIECE OF LIFE AND DEATH,” INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 9, no. 2, pp. 335–352, 2011, [Online]. Available: https://sid.ir/paper/297486/en

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