A SURVEY ON FREQUENCY RATE OF CYSTS CAUSED BY GNRH-AGANISTS IN A LONG PROTOCOL FOR IVF AND RELATED FACTORS IN ROYAN INSTITUTE

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OWJ M.; HABIBI MOEINI M.

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Journal: Daneshvar Medicine: Basic and Clinical Research Journal Year:2002 | Volume:10 | Issue:41 (Special Edition on Medical Sciences Articles) Page(s): 1-4

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Title

A SURVEY ON FREQUENCY RATE OF CYSTS CAUSED BY GNRH-AGANISTS IN A LONG PROTOCOL FOR IVF AND RELATED FACTORS IN ROYAN INSTITUTE

Author(s)

OWJ M. | HABIBI MOEINI M. | Issue Writer Certificate

Keywords

GNRH-AGONISTQ4

CYST FORMATIONQ2

IN VITRO FERTILIZATIONQ2

Abstract

The introduction of GnRH-a in to the IVF field was a modern management which reduced premature LH-surge from 20% to 2% and improved the results of ovarian stimulation and its outcome during IVF cycles. However administration of GnRH-a is associated with ovarian CYST FORMATION about 8-50% (22). The mechanism of CYST FORMATION after GnRH-a administration is not fully understood. Some authors suggested that this phenomenon may be related to the release of Gondadotropins due to the initial up regulation or flare phase. Relation between these cycst, age and basal FSH are controversial. The aims of this study are assessment of frequency rate and relation between these factors (Age and basal Hormones) and CYST FORMATION during suppression phase. 491 patient who underwent IVF or ICSI in a long protocol, were studied retrospectively. In all of whom after performing trans-vaginal sonography (TVS) on 21st day Busereline cycle, of was started (suprefact 0.5ccdaily, subcutaneous) and after, 2 weeks another TVS was done for evaluation of suppression. (Endometrial thickness <6mm+quiet ovaries or Estradiol <50 pg/ml). Cystis structures ≥20mm defined were as cysts. After complete suppression, stimulation was started as routinely in a long protocol. Age and basal FSH were recorded compared and between two groups (with cyst and without cyst) using X2, t test and Fishers exact test. results: The overall frequency rate of CYST FORMATION in our patients population was 9.5%, There were no significant differences between two groups in the age (30.4±5.7 in group with cyst vs 30.8±5.7 in group without cyst) and basal FSH (6.01±3.4 in group with cyst vs 30.8±5.7 in group without cyst) and The overall frequency rate of CYST FORMATION in our patient population (9.5%) was in the lower range reported by the researcher (8-50%). This likely is due to a number of variables including follicular or luteal phase initiation of Buserlein and the cut off for the cysts diameter. Although some studies have shown age and basal FSH (the two important indices for ovarian response) have positive correlation with CYST FORMATION, this study didn’t show any relation between them. Further studies are needed to determine whether these cysts have any effect on IVF outcome or not.

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APA: Copy

OWJ, M., & HABIBI MOEINI, M.. (2002). A SURVEY ON FREQUENCY RATE OF CYSTS CAUSED BY GNRH-AGANISTS IN A LONG PROTOCOL FOR IVF AND RELATED FACTORS IN ROYAN INSTITUTE. DANESHVAR MEDICINE, 10(41 (Special Edition on Medical Sciences Articles)), 1-4. SID. https://sid.ir/paper/30494/en

Vancouver: Copy

OWJ M., HABIBI MOEINI M.. A SURVEY ON FREQUENCY RATE OF CYSTS CAUSED BY GNRH-AGANISTS IN A LONG PROTOCOL FOR IVF AND RELATED FACTORS IN ROYAN INSTITUTE. DANESHVAR MEDICINE[Internet]. 2002;10(41 (Special Edition on Medical Sciences Articles)):1-4. Available from: https://sid.ir/paper/30494/en

IEEE: Copy

M. OWJ, and M. HABIBI MOEINI, “A SURVEY ON FREQUENCY RATE OF CYSTS CAUSED BY GNRH-AGANISTS IN A LONG PROTOCOL FOR IVF AND RELATED FACTORS IN ROYAN INSTITUTE,” DANESHVAR MEDICINE, vol. 10, no. 41 (Special Edition on Medical Sciences Articles), pp. 1–4, 2002, [Online]. Available: https://sid.ir/paper/30494/en

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