NO CORRELATION BETWEEN INTERLEUKIN-10 GENE PROMOTER POLYMORPHISMS AND HEPATITIS B VIRUS INFECTION OUTCOME

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOFIAN MASOOMEH; KALANTARI EBRAHIM; AGHAKHANI AREZOO; HOSSEINI SOUDABEH; BANIFAZL MOHAMMAD; ESLAMIFAR ALI; JOURABCHI ALI; FARAZI ALI ASGHAR; RAMEZANI AMITIS

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Hepatitis Monthly Year:2013 | Volume:13 | Issue:5 Page(s): 1-6

Download Full-Text

View:

395

Download:

Cites:

Information Journal Paper

Title

NO CORRELATION BETWEEN INTERLEUKIN-10 GENE PROMOTER POLYMORPHISMS AND HEPATITIS B VIRUS INFECTION OUTCOME

Author(s)

Keywords

HEPATITIS B VIRUS

GENOTYPE

INTERLEUKIN-10

HAPLOTYPES

Abstract

Background: Single nucleotide polymorphisms (SNP) in the promoter region of the interleukin (IL)-10 genes have a role in determining HEPATITIS B VIRUS (HBV) outcome.Objectives: This study evaluates the correlation between HBV infection and SNP in IL-10 gene promoter.Patients and Methods: Ninety-six HBV-infected patients (32 chronic hepatitis B infection patients, 34 healthy carriers, 30 spontaneously recovered cases) and 31 healthy controls were enrolled. Three biallelic (-819, -592, -1082) regions in the IL-10 gene promoter were sequenced for all patients. Results: GENOTYPEs and HAPLOTYPES of IL-10 gene promoter region at position -1082, -819 and -592 were not significantly different among controls, HBV recovered cases, carriers and chronic HBV patients. Nevertheless, A/A GENOTYPE at position -592 and T/T GENOTYPE at position -819 were more frequently seen in the HBV clearance group, while frequency of G/G GENOTYPE at position -1082 was more prevalent in the persistence group. GCC/GCC and GCC/ACC HAPLOTYPES were significantly observed in anti-HBe positive individuals.Conclusions: Our findings showed that IL-10 promoter polymorphisms were not correlated with HBV infection prognosis. Nevertheless, individuals carrying high and intermediate producer of IL-10 HAPLOTYPES had a better ability to develop anti-HBe than low producer carriers.

Cites

References

No record.

Cite

APA: Copy

SOFIAN, MASOOMEH, KALANTARI, EBRAHIM, AGHAKHANI, AREZOO, HOSSEINI, SOUDABEH, BANIFAZL, MOHAMMAD, ESLAMIFAR, ALI, JOURABCHI, ALI, FARAZI, ALI ASGHAR, & RAMEZANI, AMITIS. (2013). NO CORRELATION BETWEEN INTERLEUKIN-10 GENE PROMOTER POLYMORPHISMS AND HEPATITIS B VIRUS INFECTION OUTCOME. HEPATITIS MONTHLY, 13(5), 1-6. SID. https://sid.ir/paper/306840/en

Vancouver: Copy

SOFIAN MASOOMEH, KALANTARI EBRAHIM, AGHAKHANI AREZOO, HOSSEINI SOUDABEH, BANIFAZL MOHAMMAD, ESLAMIFAR ALI, JOURABCHI ALI, FARAZI ALI ASGHAR, RAMEZANI AMITIS. NO CORRELATION BETWEEN INTERLEUKIN-10 GENE PROMOTER POLYMORPHISMS AND HEPATITIS B VIRUS INFECTION OUTCOME. HEPATITIS MONTHLY[Internet]. 2013;13(5):1-6. Available from: https://sid.ir/paper/306840/en

IEEE: Copy

MASOOMEH SOFIAN, EBRAHIM KALANTARI, AREZOO AGHAKHANI, SOUDABEH HOSSEINI, MOHAMMAD BANIFAZL, ALI ESLAMIFAR, ALI JOURABCHI, ALI ASGHAR FARAZI, and AMITIS RAMEZANI, “NO CORRELATION BETWEEN INTERLEUKIN-10 GENE PROMOTER POLYMORPHISMS AND HEPATITIS B VIRUS INFECTION OUTCOME,” HEPATITIS MONTHLY, vol. 13, no. 5, pp. 1–6, 2013, [Online]. Available: https://sid.ir/paper/306840/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops