HEDGEHOG SIGNALLING PATHWAY: CARCINOGENESIS AND TARGETED THERAPY (REVIEW ARTICLE)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

EBRAHIMI ABDOLALI; LARIJANI LEILA; MORADI AFSHIN; EBRAHIMI MOHAMAD REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: INTERNATIONAL JOURNAL OF CANCER MANAGEMENT Year:2013 | Volume:6 | Issue:1 Page(s): 36-43

Download Full-Text

View:

343

Download:

140

Cites:

Information Journal Paper

Title

HEDGEHOG SIGNALLING PATHWAY: CARCINOGENESIS AND TARGETED THERAPY (REVIEW ARTICLE)

Author(s)

EBRAHIMI ABDOLALI | LARIJANI LEILA | MORADI AFSHIN | EBRAHIMI MOHAMAD REZA | Issue Writer Certificate

Keywords

HEDGEHOG

NEOPLASM

MOLECULAR TARGETED THERAPY

Abstract

Hedgehog signalling pathway has not only a critical role in cell proliferation, differentiation and tissue polarity at embryonic period but also has a vital role in stem cell proliferation, tissue healing and carcinogenesis. Recent research has increased our understanding of this pathway and its relation to other signaling pathways. In addition, a large number of studies confirmed the alteration of Hh signalling pathway in various types of human malignancies including basal cell carcinomas, medulloblastomas, lung, gastrointestinal, ovarian, breast, prostate cancers and leukemia. More than 50 small biomolecules have been introduced which have inhibitory effects on Hh signalling pathway. Although, in many tumors some acceptable results have been showed in phase I clinical trial, closer studies are required to improve drug bioavailability, to decrease the side effects and to find the right small molecules for specific types of cancers, considering patients overall benefits as well.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

EBRAHIMI, ABDOLALI, LARIJANI, LEILA, MORADI, AFSHIN, & EBRAHIMI, MOHAMAD REZA. (2013). HEDGEHOG SIGNALLING PATHWAY: CARCINOGENESIS AND TARGETED THERAPY (REVIEW ARTICLE). INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), 6(1), 36-43. SID. https://sid.ir/paper/312552/en

Vancouver: Copy

EBRAHIMI ABDOLALI, LARIJANI LEILA, MORADI AFSHIN, EBRAHIMI MOHAMAD REZA. HEDGEHOG SIGNALLING PATHWAY: CARCINOGENESIS AND TARGETED THERAPY (REVIEW ARTICLE). INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION)[Internet]. 2013;6(1):36-43. Available from: https://sid.ir/paper/312552/en

IEEE: Copy

ABDOLALI EBRAHIMI, LEILA LARIJANI, AFSHIN MORADI, and MOHAMAD REZA EBRAHIMI, “HEDGEHOG SIGNALLING PATHWAY: CARCINOGENESIS AND TARGETED THERAPY (REVIEW ARTICLE),” INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), vol. 6, no. 1, pp. 36–43, 2013, [Online]. Available: https://sid.ir/paper/312552/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops