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Cites:

1

Information Journal Paper

Title

The Effects of Six Weeks Endurance Training on XBP-1 Protein in the Diabetic Male Wistar Rats Sciatica Tissues

Pages

  187-193

Abstract

 Objective: The aim of this study was to investigate the effect of endurance activity on XBP-1 protein content in sciatica tissue of diabetic male Wistar rats. Materials and Methods: The experimental design was a posttest design with control group. In this study, 32 male Wistar 10 weeks old rats with the mean weight of 253. 16 (± 10. 16) grams were randomly divided into four groups: healthy control, healthy exercise, diabetic control and diabetic training group. An intraperitoneal injection of STZ (45 mg / kg) solution was used to induce Diabetes after 12 hours fasting, 48 hours after STZ injection, the moderateintensity endurance protocol was performed for 6 weeks. Twentyfour hours after the last training session, the mice were exposed and their Sciatic nerve was extracted. The amount of XBP-1 protein was measured by ELISA method. For statistical analysis, SPSS software and two-way ANOVA with repeated measure and independent T-test were used. Results: Data analysis showed that endurance activity had an effect on the amount of XBP-1 protein and reduced the protein content, so that the difference was significant in the diabetic training group compared to the diabetic control group (P-value: 0. 007). Conclusion: These findings indicated that moderate aerobic exercise has a significant effect on the amount of XBP-1 protein in healthy and diabetic rats.

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    • Cite

    APA: Copy

    Hamedifar, Mohamad, MIRNASURI, RAHIM, & RAHMATI, MASOUD. (2018). The Effects of Six Weeks Endurance Training on XBP-1 Protein in the Diabetic Male Wistar Rats Sciatica Tissues. IRANIAN JOURNAL OF DIABETES AND OBESITY, 10(4), 187-193. SID. https://sid.ir/paper/318237/en

    Vancouver: Copy

    Hamedifar Mohamad, MIRNASURI RAHIM, RAHMATI MASOUD. The Effects of Six Weeks Endurance Training on XBP-1 Protein in the Diabetic Male Wistar Rats Sciatica Tissues. IRANIAN JOURNAL OF DIABETES AND OBESITY[Internet]. 2018;10(4):187-193. Available from: https://sid.ir/paper/318237/en

    IEEE: Copy

    Mohamad Hamedifar, RAHIM MIRNASURI, and MASOUD RAHMATI, “The Effects of Six Weeks Endurance Training on XBP-1 Protein in the Diabetic Male Wistar Rats Sciatica Tissues,” IRANIAN JOURNAL OF DIABETES AND OBESITY, vol. 10, no. 4, pp. 187–193, 2018, [Online]. Available: https://sid.ir/paper/318237/en

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