Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ASLANI ABOLFAZL; ZOLFAGHARI BEHZAD; Fereidani Yeganeh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DENTAL RESEARCH JOURNAL Year:2018 | Volume:15 | Issue:3 Page(s): 191-200

Download Full-Text

View:

154

Download:

195

Cites:

Information Journal Paper

Title

Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections

Author(s)

ASLANI ABOLFAZL | ZOLFAGHARI BEHZAD | Fereidani Yeganeh | Issue Writer Certificate

Keywords

Herpes labialis

licorice

melissa

rosemary

sumac

Abstract

Background: The herpes simplex virus is a human pathogen which can cause skin or mucous membrane infections. Melissa, sumac, licorice, rosemary, and geranium have antimicrobial, antiviral, anti‑ inflammatory, and local analgesic effect. Shortening recovery period of recurrent herpes labialis and control of viral protein formation are the other effects of these herbs. The aim of this study is design, formulation, and evaluation of the gel containing extracts of these five herbs. Materials and Methods: In this experimental study after photochemical and macroscopic evaluation of these medicinal herbs, the semisolid concentrated extracts were incorporated in gel bases. Mucoadhesive gels were prepared using carbopol 940, sodium carboxymethylcellulose (Na CMC) and hydroxypropyl methylcellulose K4M as bioadhesive polymers. Physicochemical tests, viscosity, mucoadhesive strength measurement, and in vitro drug release study were carried out on formulations F10 (carbopol 940, 0. 5% and Na CMC, 3%) and F11 (carbopol 940, 1% and Na CMC, 3%). Results: Polyphenol content of extracts mixture was measured 210. 8 ± 13. 68 mg GAE/g. pH of formulations was 6. 0 ± 0. 2. 14 gel formulations were prepared. Physical appearance, homogeneity, and consistency of F10 and F11 were good. Mucoadhesion and viscosity of F11 was more than F10. Study of release profiles in F10 and F11 formulations showed drug release from F11 was slower. Conclusion: The best formulation for treatment and shortening recovery period of recurrent labial herpes infections should exhibit high value of mucoadhesion, show controlled release of drug. F11 with the highest viscosity and mucoadhesion and the lowest release rate was considered as the best formulation.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

ASLANI, ABOLFAZL, ZOLFAGHARI, BEHZAD, & Fereidani, Yeganeh. (2018). Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections. DENTAL RESEARCH JOURNAL, 15(3), 191-200. SID. https://sid.ir/paper/325135/en

Vancouver: Copy

ASLANI ABOLFAZL, ZOLFAGHARI BEHZAD, Fereidani Yeganeh. Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections. DENTAL RESEARCH JOURNAL[Internet]. 2018;15(3):191-200. Available from: https://sid.ir/paper/325135/en

IEEE: Copy

ABOLFAZL ASLANI, BEHZAD ZOLFAGHARI, and Yeganeh Fereidani, “Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections,” DENTAL RESEARCH JOURNAL, vol. 15, no. 3, pp. 191–200, 2018, [Online]. Available: https://sid.ir/paper/325135/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops