مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

Review Article: Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders

Pages

  195-212

Abstract

 Objective: Black cumin or Nigella sativa (N. sativa) seed has been widely used traditionally as a medicinal natural product because of its therapeutic effects. In this review, the medicinal properties of N. sativa as a healing remedy for the treatment of respiratory and Allergic diseases, were evaluated. Material and Methods: Keywords including Nigella sativa, black seed, Thymoquinone, respiratory, pulmonary, lung and Allergic diseases were searched in medical and nonmedical databases (i. e. PubMed, Science Direct, Scopus, and Google Scholar). Preclinical studies and clinical trials published between 1993 and 2018 were selected. Results: In experimental and clinical studies, antioxidant, immunomodulatory, anti-inflammatory, antihistaminic, antiallergic, antitussive and bronchodilatory properties of N. sativa different extracts, extracts fractions and constituents were demonstrated. Clinical studies also showed bronchodilatory and preventive properties of the plant in asthmatic patients. The extract of N. sativa showed a preventive effect on lung disorders caused by sulfur mustard exposure. The therapeutic effects of the plant and its constituents on various allergic disorders were also demonstrated. Conclusion: Therefore, N. sativa and its constituents may be considered effective remedies for treatment of allergic and obstructive lung diseases as well as other Respiratory diseases.

Cites

References

Cite

APA: Copy

GHOLAMNEZHAD, ZAHRA, SHAKERI, FARZANEH, SAADAT, SAEIDEH, Ghorani, Vahideh, & BOSKABADY, MOHAMMAD HOSSEIN. (2019). Review Article: Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 9(3), 195-212. SID. https://sid.ir/paper/326516/en

Vancouver: Copy

GHOLAMNEZHAD ZAHRA, SHAKERI FARZANEH, SAADAT SAEIDEH, Ghorani Vahideh, BOSKABADY MOHAMMAD HOSSEIN. Review Article: Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2019;9(3):195-212. Available from: https://sid.ir/paper/326516/en

IEEE: Copy

ZAHRA GHOLAMNEZHAD, FARZANEH SHAKERI, SAEIDEH SAADAT, Vahideh Ghorani, and MOHAMMAD HOSSEIN BOSKABADY, “Review Article: Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders,” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 9, no. 3, pp. 195–212, 2019, [Online]. Available: https://sid.ir/paper/326516/en

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