EVALUATION OF HELICOBATER PYLORI CAGA GENE RELATIONSHIP AND ENDOSCOPIC FINDINGS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHOKOUHIZADEH L.; MOHABATI MOBAREZ A.; SADEGHIZADEH M.; AMINI MOHSEN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: KOWSAR MEDICAL JOURNAL Year:2006 | Volume:11 | Issue:3 Page(s): 261-266

Download Full-Text

Persian Verion

View:

1,048

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF HELICOBATER PYLORI CAGA GENE RELATIONSHIP AND ENDOSCOPIC FINDINGS

Author(s)

SHOKOUHIZADEH L. | MOHABATI MOBAREZ A. | SADEGHIZADEH M. | AMINI MOHSEN | Issue Writer Certificate

Keywords

HELICOBACTER PYLORIQ3

UREASEQ3

GASTRIC BIOPSYQ3

GASTRIC ULCERQ3

DUODENAL ULCERQ3

ESOPHAGITISQ3

CAGAQ3

URECQ3

PCRQ3

Abstract

Aim: There are controversial findings about the role of CAGA gene in H. pylori infection. The aim of this study was to determine the prevalence of CAGA+ strain of HELICOBACTER PYLORI and to evaluate its correlation with endoscopic findings. Materials and methods: Of 152 gastric biopsies taken by endoscopy in Baghiatallah hospital, Tehran-Iran, positive samples of H. Pylori were detected by rapid UREASE test.Results were confirmed by PCR using the UREC primers. Using designed primers for CAGA gene amplification, CAGA positive and negative strains were detected and endoscopic findings between them were compared.Results: 54 cases (35.5%) were H. pylori positive. Among them, the prevalence of CAGA gene was 35.18% (19 cases). In CAGA+ strains, frequencies of atrophic gastritis, GASTRIC ULCER, duodenal deformity and DUODENAL ULCER were higher than those in CAGA strains.There was reverse correlation between the presence of CAGA gene and the severity of ESOPHAGITIS.Conclusion: Due to increasing rates of H.pylori infection and in order to decrease treatment cost and limitation of culture as a gold standard method. The results suggest the PCR method using CAGA and UREC based primer, as a sensitive and rapid method for diagnosing of H.pylori between clinical isolates.

Cites

ASSESSMENT THE RELATIONSHIP OF CAGA GENE WITH DIFFERENT GASTRODUODENAL DISEASES IN HELICOBACTER PYLORI INFECTED PATIENTS

References

No record.

Cite

APA: Copy

SHOKOUHIZADEH, L., MOHABATI MOBAREZ, A., SADEGHIZADEH, M., & AMINI, MOHSEN. (2006). EVALUATION OF HELICOBATER PYLORI CAGA GENE RELATIONSHIP AND ENDOSCOPIC FINDINGS. KOWSAR MEDICAL JOURNAL, 11(3), 261-266. SID. https://sid.ir/paper/32717/en

Vancouver: Copy

SHOKOUHIZADEH L., MOHABATI MOBAREZ A., SADEGHIZADEH M., AMINI MOHSEN. EVALUATION OF HELICOBATER PYLORI CAGA GENE RELATIONSHIP AND ENDOSCOPIC FINDINGS. KOWSAR MEDICAL JOURNAL[Internet]. 2006;11(3):261-266. Available from: https://sid.ir/paper/32717/en

IEEE: Copy

L. SHOKOUHIZADEH, A. MOHABATI MOBAREZ, M. SADEGHIZADEH, and MOHSEN AMINI, “EVALUATION OF HELICOBATER PYLORI CAGA GENE RELATIONSHIP AND ENDOSCOPIC FINDINGS,” KOWSAR MEDICAL JOURNAL, vol. 11, no. 3, pp. 261–266, 2006, [Online]. Available: https://sid.ir/paper/32717/en

Related Journal Papers