HEMATOLOGIC FEATURES OF ALPHA THALASSEMIA CARRIERS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AKHAVAN NIAKI HALEH; YOUSSEFI KAMANGARI REZA; BANIHASHEMI ALI; KHOLGHI OSKOOEI VAHID; AZIZI MANDANA; TAMADDONI AHMAD; SEDAGHAT SADEGH; MAHMOUDI NESHELI HASSAN; SHABANI SORAYA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Molecular and Cellular Medicine Year:2012 | Volume:1 | Issue:3 Page(s): 162-167

Download Full-Text

View:

367

Download:

200

Cites:

Information Journal Paper

Title

HEMATOLOGIC FEATURES OF ALPHA THALASSEMIA CARRIERS

Author(s)

Keywords

ALPHA THALASSEMIA

MEAN CELL VOLUME

MEAN CELL HEMOGLOBIN

MUTATION

Abstract

ALPHA THALASSEMIA (a-thal) is relatively common worldwide. Most carriers are defective in either one or two alpha globin genes out of four functional ones, with deletions being more common than point MUTATIONs. The hematologic features are very important for the selection of the appropriate molecular tests while determining the genotype. The aim of this study was to compare hematologic features of patients with various types of a globin MUTATIONs. Hematological indices including red blood cells (RBC), hemoglobin concentration (Hb), MEAN CELL VOLUME (MCV), MEAN CELL HEMOGLOBIN (MCH), Mean corpuscular hemoglobin concentration (MCHC) and percentage of Hemoglobin (HBA1, HBA2 and HBF) of seven-hundred and twenty two patients presenting ten different a-thal genotypes were considered. All patients showed reduced MCV and/or MCH values. Moreover, MCV and MCH were lower in patients with two functional alpha globin genes in comparison to patients with one mutated alpha globin gene (P value<0.001). In conclusion, MCV and MCH values can be helpful for the selection of the appropriate molecular tests to determine the genotype of ALPHA THALASSEMIA carriers.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

AKHAVAN NIAKI, HALEH, YOUSSEFI KAMANGARI, REZA, BANIHASHEMI, ALI, KHOLGHI OSKOOEI, VAHID, AZIZI, MANDANA, TAMADDONI, AHMAD, SEDAGHAT, SADEGH, MAHMOUDI NESHELI, HASSAN, & SHABANI, SORAYA. (2012). HEMATOLOGIC FEATURES OF ALPHA THALASSEMIA CARRIERS. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, 1(3), 162-167. SID. https://sid.ir/paper/332099/en

Vancouver: Copy

AKHAVAN NIAKI HALEH, YOUSSEFI KAMANGARI REZA, BANIHASHEMI ALI, KHOLGHI OSKOOEI VAHID, AZIZI MANDANA, TAMADDONI AHMAD, SEDAGHAT SADEGH, MAHMOUDI NESHELI HASSAN, SHABANI SORAYA. HEMATOLOGIC FEATURES OF ALPHA THALASSEMIA CARRIERS. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE[Internet]. 2012;1(3):162-167. Available from: https://sid.ir/paper/332099/en

IEEE: Copy

HALEH AKHAVAN NIAKI, REZA YOUSSEFI KAMANGARI, ALI BANIHASHEMI, VAHID KHOLGHI OSKOOEI, MANDANA AZIZI, AHMAD TAMADDONI, SADEGH SEDAGHAT, HASSAN MAHMOUDI NESHELI, and SORAYA SHABANI, “HEMATOLOGIC FEATURES OF ALPHA THALASSEMIA CARRIERS,” INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, vol. 1, no. 3, pp. 162–167, 2012, [Online]. Available: https://sid.ir/paper/332099/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops