EFFECT OF 8 WEEKS RESISTANCE TRAINING ON PLASMA LEVELS OF NERVE GROWTH FACTOR AND INTERLUKIN-6 IN FEMALE PATIENTS WITH MULTIPLE SCLEROSIS

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MOGHADASI M.; EDALATMANESH M.A.; MOEINI A.; NEMATOLLAHZADEH MAHANI M.; ARVIN H.

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Journal: Iranian South Medical Journal Year:2015 | Volume:18 | Issue:3 Page(s): 527-537

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Title

EFFECT OF 8 WEEKS RESISTANCE TRAINING ON PLASMA LEVELS OF NERVE GROWTH FACTOR AND INTERLUKIN-6 IN FEMALE PATIENTS WITH MULTIPLE SCLEROSIS

Author(s)

Keywords

RESISTANCE TRAININGQ1

MULTIPLE SCLEROSISQ1

NERVE GROWTH FACTORQ2

INTERLUKINQ2

6Q2

Abstract

Background: In recent years, evidence from a number of studies has suggested that exercise is a safe and efficient way to induce improvements in a number of physiological functions in MULTIPLE SCLEROSIS (MS) patients, but the effects of exercise on NERVE GROWTH FACTOR (NGF) and INTERLUKIN-6 (IL-6) in these patients are not well known. Thus, the purpose of this study was to evaluate the effect of 8 weeks RESISTANCE TRAINING on plasma NGF and IL-6 in female patients with MS.Materials and methods: Thirty two female MS patients with 32.4±5.5 years of old, and expanded disability status scale (EDSS) 0-4.5, participated in this study. The subjects were randomly assigned to control group (n=13) and training group (n=14). Subjects in training group performed selected upper and lower extremities RESISTANCE TRAINING with weight-training equipment and rubber bands 3 days a week for 8 weeks. Body composition parameters, NGF and IL-6 levels were measured before and after the intervention.Results: The results showed that body weight, body mass index, body fat mass and EDSS were decreased significantly after 8 weeks in training group compared to control group (P<0.05). Also, no significant differences were seen after the intervention in NGF and IL-6 between the training and control groups.Conclusion: The results suggest RESISTANCE TRAINING with specific intensity and duration utilized in this study improves EDSS in female patients with MS but it has no effecting on NGF and IL-6 in these patients.

Cites

THE EFFECT OF SWIMMING EXERCISE WITH INJECTIONS OF VITAMIN D SUPPLEMENTATION ON THE LEVELS OF NERVE GROWTH FACTOR (NGF) IN THE BRAIN TISSUE OF FEMALE RATS WITH EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS

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APA: Copy

MOGHADASI, M., EDALATMANESH, M.A., MOEINI, A., NEMATOLLAHZADEH MAHANI, M., & ARVIN, H.. (2015). EFFECT OF 8 WEEKS RESISTANCE TRAINING ON PLASMA LEVELS OF NERVE GROWTH FACTOR AND INTERLUKIN-6 IN FEMALE PATIENTS WITH MULTIPLE SCLEROSIS. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 18(3), 527-537. SID. https://sid.ir/paper/33588/en

Vancouver: Copy

MOGHADASI M., EDALATMANESH M.A., MOEINI A., NEMATOLLAHZADEH MAHANI M., ARVIN H.. EFFECT OF 8 WEEKS RESISTANCE TRAINING ON PLASMA LEVELS OF NERVE GROWTH FACTOR AND INTERLUKIN-6 IN FEMALE PATIENTS WITH MULTIPLE SCLEROSIS. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2015;18(3):527-537. Available from: https://sid.ir/paper/33588/en

IEEE: Copy

M. MOGHADASI, M.A. EDALATMANESH, A. MOEINI, M. NEMATOLLAHZADEH MAHANI, and H. ARVIN, “EFFECT OF 8 WEEKS RESISTANCE TRAINING ON PLASMA LEVELS OF NERVE GROWTH FACTOR AND INTERLUKIN-6 IN FEMALE PATIENTS WITH MULTIPLE SCLEROSIS,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 18, no. 3, pp. 527–537, 2015, [Online]. Available: https://sid.ir/paper/33588/en

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