DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN AND EXTENDED-SPECTRUM BETA LACTAMASES PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM CLINICAL SPECIMENS OF HAJAR AND KASHANI HOSPITALS, SHAHREKORD 1387

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHOJAPOUR M.; VALIDI M.; SHARIATI L.; ZAMANZAD B.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2011 | Volume:4 | Issue:2 Page(s): 94-99

Download Full-Text

Persian Verion

View:

836

Download:

Cites:

Information Journal Paper

Title

DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN AND EXTENDED-SPECTRUM BETA LACTAMASES PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM CLINICAL SPECIMENS OF HAJAR AND KASHANI HOSPITALS, SHAHREKORD 1387

Author(s)

SHOJAPOUR M. | VALIDI M. | SHARIATI L. | ZAMANZAD B. | Issue Writer Certificate

Keywords

ANTIBIOTIC RESISTANCEQ3

COMBINED DISK METHODQ2

ESBLSQ2

PSEUDOMONAS AERUGINOSAQ2

Abstract

Background: PSEUDOMONAS AERUGINOSA is one of the leading causes of hospital infections in patients hospitalized for a 10 day period or over. It is also considered to be the most important cause of the burn wound infection. Approximately 75% of deaths in burned patients are due to wound infection and the subsequent septicemia. Clinical use of antibiotics has increasingly led to the global distribution of P. aeruginosa isolates with multi-drug resistance. The study was launched to determine the antimicrobial susceptibility pattern and the presence of the extended-spectrum-beta lactamase (ESBL) in P.aeruginosa strains isolated from clinical specimens.Methods: Totally, 175 P. aeruginosa strains were isolated from clinical samples and identified by standard methods. The pattern of antimicrobial resistance was then performed on the isolates using Disk Agar Diffusion (DAD) according to CLSI Guideline. Primary screening test for ESBL producing strains was performed by ceftazidim antibiotic disk using disk diffusion method. COMBINED DISK METHOD was used to confirm ESBL producing bacteria.Results: The rate of antimicrobial resistance of P.aeruginosa isolates were 64% to ticarcillin, 52.2% to cefepime, 68.6% to ticarcillin/clavolanic acid, 68.6% to ceftazidime, 67.4% to amikacin, 68.6% to gentamicin, 48% to imipenem, 77.7% to ciprofloxacin and 5.1% to polymixcine B. In the primary screening test, 120 isolates of P.aeruginosa strains were resistant to ceftazidime. In the COMBINED DISK METHOD, 66 isolates (55%) were positive for ESBLS.Conclusion: Polymixcine B was found to be the most effective antimicrobial agent in this study. Bacteria carrying ESBL genes may increase mortality and morbidity. Thus, their accurate diagnosis is of extreme importance to prevent from the treatment failure resulted from improper antibiotic administration.

Cites

No record.

References

No record.

Cite

APA: Copy

SHOJAPOUR, M., VALIDI, M., SHARIATI, L., & ZAMANZAD, B.. (2011). DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN AND EXTENDED-SPECTRUM BETA LACTAMASES PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM CLINICAL SPECIMENS OF HAJAR AND KASHANI HOSPITALS, SHAHREKORD 1387. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 4(2), 94-99. SID. https://sid.ir/paper/33747/en

Vancouver: Copy

SHOJAPOUR M., VALIDI M., SHARIATI L., ZAMANZAD B.. DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN AND EXTENDED-SPECTRUM BETA LACTAMASES PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM CLINICAL SPECIMENS OF HAJAR AND KASHANI HOSPITALS, SHAHREKORD 1387. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2011;4(2):94-99. Available from: https://sid.ir/paper/33747/en

IEEE: Copy

M. SHOJAPOUR, M. VALIDI, L. SHARIATI, and B. ZAMANZAD, “DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN AND EXTENDED-SPECTRUM BETA LACTAMASES PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM CLINICAL SPECIMENS OF HAJAR AND KASHANI HOSPITALS, SHAHREKORD 1387,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 4, no. 2, pp. 94–99, 2011, [Online]. Available: https://sid.ir/paper/33747/en

Related Journal Papers