Seizure Prevalence and Its Related Factors in Tramadol Intoxication; a Brief Report (BRIEF REPORT)

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Babahajian Asrin; KHOMAND PAYAM; Manoochehri Farhad; Fakhimi Roozbeh; AHSAN BEHROOZ; Amjadian Mohiadin; Yousefinejad Vahid

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Journal: Archives of Academic Emergency Medicine Year:2019 | Volume:7 | Issue:1 Page(s): 0-0

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Title

Seizure Prevalence and Its Related Factors in Tramadol Intoxication; a Brief Report (BRIEF REPORT)

Author(s)

Keywords

Tramadol

seizure

toxicity

emergency service

hospital

risk factor

Abstract

Introduction: seizure is known to be a serious complication of Tramadol consumption even in its therapeutic doses. The aim of this study was to determine the prevalence of seizure and its related factors in Tramadol intoxicated patients referred to emergency department (ED). Methods: In this cross-sectional study, all individuals, admitted to ED following Tramadol intoxication were divided into two groups based on the presence or absence of seizures. Demographic data as well as clinical, electroencephalogram and imaging findings were compared between the two groups using SPSS software version 22. Results: 167 patients with the median age of 23 (13-45) years were studied (85% male). seizure was seen in 97 (58. 0%) cases. Risk of seizure had increased 3. 7 times in patients with a history of seizure (OR: 3. 71 Cl 95%: 1. 17-11. 76). Tramadol dose was significantly higher in patients who had seizuremore than once (Median: 2800 IQR: 1800-4000), compared to those who had one seizure episode (Median: 850 IQR: 1800-400) (p <0. 0001). Conclusion: Based on the findings of this study, history of seizure increased the risk of seizure in patients taking Tramadol, and the increase in dose correlated with a significant increase in seizure frequency.

Cites

Seizure Prediction Model in Acute Tramadol Poisoning; a Derivation and Validation study

References

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APA: Copy

Babahajian, Asrin, KHOMAND, PAYAM, Manoochehri, Farhad, Fakhimi, Roozbeh, AHSAN, BEHROOZ, Amjadian, Mohiadin, & Yousefinejad, Vahid. (2019). Seizure Prevalence and Its Related Factors in Tramadol Intoxication; a Brief Report (BRIEF REPORT). ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY), 7(1), 0-0. SID. https://sid.ir/paper/339823/en

Vancouver: Copy

Babahajian Asrin, KHOMAND PAYAM, Manoochehri Farhad, Fakhimi Roozbeh, AHSAN BEHROOZ, Amjadian Mohiadin, Yousefinejad Vahid. Seizure Prevalence and Its Related Factors in Tramadol Intoxication; a Brief Report (BRIEF REPORT). ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY)[Internet]. 2019;7(1):0-0. Available from: https://sid.ir/paper/339823/en

IEEE: Copy

Asrin Babahajian, PAYAM KHOMAND, Farhad Manoochehri, Roozbeh Fakhimi, BEHROOZ AHSAN, Mohiadin Amjadian, and Vahid Yousefinejad, “Seizure Prevalence and Its Related Factors in Tramadol Intoxication; a Brief Report (BRIEF REPORT),” ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY), vol. 7, no. 1, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/339823/en

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