THE EFFECT OF ANTIVIRAL ACTIVITY OF GREEN SEAWEED FROM THE PERSIAN GULF, CAULERPA SERTULARIOIDES ON HERPES SIMPLEX VIRUS TYPE 1

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ZANDI K.; BAHMANYAR M.; SARTAVI K.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian South Medical Journal Year:2006 | Volume:9 | Issue:1 Page(s): 1-8

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Title

THE EFFECT OF ANTIVIRAL ACTIVITY OF GREEN SEAWEED FROM THE PERSIAN GULF, CAULERPA SERTULARIOIDES ON HERPES SIMPLEX VIRUS TYPE 1

Author(s)

ZANDI K. | BAHMANYAR M. | SARTAVI K. | Issue Writer Certificate

Keywords

CAULERPASERTULARIOIDESQ3

HERPES SIMPLEX VIRUS TYPE 1Q3

SEAWEEDQ2

INFECTIVITYQ3

Abstract

Background: By considering the daily increase in drug resistance of various viruses, novel antiviral compounds extracted from natural resources-due to their fewer side effects, had always been important to researchers. In the present study, we investigated antiviral activity of the hot water extract of green SEAWEED, Caulerpa sertularioides, collected from coastal water of Bushehr in the Persian Gulf, against Herpes Simplex Virus Type I (HSV-1).Methods: The hot water extract of green SEAWEED, Caulerpa sertularioides was sterilized by autoclave and filtration methods. After determining its cytotoxic concentration 50 (CC50) value, the effect of the extract on the inhibition of HSV-1 replication was examined in Vero cell culture.Results: The extract showed antiviral activity against HSV-1 in both attachment and entry of virus to the Vero cells and also on post attachment stages of virus replication. Inhibitory concentration 50 (IC50) values of the autoclaved extract were 81µg/ml and 126µg/ml for attachment and post attachment stages, respectively. IC50 values of the filtered extract were 73µg/ml and 104µg/ml for attachment and post attachment stages, respectively. CC50 values for autoclaved and filtered extracts were 3140 µg/ml and 3095 µg/ml, respectively.Conclusion: The hot water extract of Caulerpa sertularioides of the Persian Gulf had antiviral effect against HSV-1.

Cites

ALGA CULTURAL SURVEY ON THREE SPECIES: SARGASSUM ILICIFOLIUM, HYPNEA MUSCIFORMIS AND CYSTOSEIRA INDICA IN CHABAHAR SEASHORE, IRAN

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APA: Copy

ZANDI, K., BAHMANYAR, M., & SARTAVI, K.. (2006). THE EFFECT OF ANTIVIRAL ACTIVITY OF GREEN SEAWEED FROM THE PERSIAN GULF, CAULERPA SERTULARIOIDES ON HERPES SIMPLEX VIRUS TYPE 1. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 9(1), 1-8. SID. https://sid.ir/paper/34067/en

Vancouver: Copy

ZANDI K., BAHMANYAR M., SARTAVI K.. THE EFFECT OF ANTIVIRAL ACTIVITY OF GREEN SEAWEED FROM THE PERSIAN GULF, CAULERPA SERTULARIOIDES ON HERPES SIMPLEX VIRUS TYPE 1. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2006;9(1):1-8. Available from: https://sid.ir/paper/34067/en

IEEE: Copy

K. ZANDI, M. BAHMANYAR, and K. SARTAVI, “THE EFFECT OF ANTIVIRAL ACTIVITY OF GREEN SEAWEED FROM THE PERSIAN GULF, CAULERPA SERTULARIOIDES ON HERPES SIMPLEX VIRUS TYPE 1,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 9, no. 1, pp. 1–8, 2006, [Online]. Available: https://sid.ir/paper/34067/en

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