ENDOCRINE COMPLICATIONS IN PATIENTS WITH MAJOR β-THALASSEMIA

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ROSTAMI P.; HATAMI G.; SHIRKANI A.

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Journal: Iranian South Medical Journal Year:2012 | Volume:14 | Issue:4 Page(s): 240-245

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Information Journal Paper

Title

ENDOCRINE COMPLICATIONS IN PATIENTS WITH MAJOR β-THALASSEMIA

Author(s)

ROSTAMI P. | HATAMI G. | SHIRKANI A. | Issue Writer Certificate

Keywords

βTHALASSEMIA MAJORQ3

NEUROENDOCRINE EFFECTSQ2

SHORT STATUREQ3

HYPOGONADISMQ3

HYPOTHYROIDI-SMQ3

HYPOPARATHYROIDISMQ3

Abstract

Background: Endocrine complications in patients with major b–thalassemia related to iron overload that the most important cause of mortality and morbidity in this patients. This study evaluate prevalence of endocrine complications in major b -thalassemia.Methods: Sixty patients with major b- thalassemia enrolled in this study.Results: We assessed 60 patients, including 27 men and 33 female disorders with major b- thalassemia by age range (10-44 years-old). 26.8% of patients didn’t have any endocrine disorders, 23.5% of patients one disorder and 48.7% have more than two. The most common complications of endocrine were: HYPOGONADISM (66.7%), SHORT STATURE (45%), HYPOPARATHYROIDISM (21.7%), diabet mellitus (18.3%), impaired glucose tolerance (6.7%), overt hypothyroidism (1.65%), subclinical hypothyroidism (1.65%).Conclusion: High prevalence of endocrine complications found in this study may emphasize regular endocrine assessment. In thalassemic patients especially in patients over the age of 10 years old.

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APA: Copy

ROSTAMI, P., HATAMI, G., & SHIRKANI, A.. (2012). ENDOCRINE COMPLICATIONS IN PATIENTS WITH MAJOR β-THALASSEMIA. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 14(4), 240-245. SID. https://sid.ir/paper/34178/en

Vancouver: Copy

ROSTAMI P., HATAMI G., SHIRKANI A.. ENDOCRINE COMPLICATIONS IN PATIENTS WITH MAJOR β-THALASSEMIA. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2012;14(4):240-245. Available from: https://sid.ir/paper/34178/en

IEEE: Copy

P. ROSTAMI, G. HATAMI, and A. SHIRKANI, “ENDOCRINE COMPLICATIONS IN PATIENTS WITH MAJOR β-THALASSEMIA,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 14, no. 4, pp. 240–245, 2012, [Online]. Available: https://sid.ir/paper/34178/en

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