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Information Journal Paper

Title

Critical Roles of Non-coding RNAs in Acute Lymphoblastic Leukemia

Pages

  0-0

Abstract

 MicroRNA (all&fgrp=all&fyrs=all" target="_blank">miRNA) is one of the non-codingRNA(all&fgrp=all&fyrs=all" target="_blank">ncRNA) molecules with 21-25-nucleotide length, playing an important role in gene control by transcriptional gene regulation, chromatin remodeling, genetic imprinting, and translation initiation. The deregulation of all&fgrp=all&fyrs=all" target="_blank">ncRNA can lead to several hematopoietic malignancies such as acute lymphoblastic leukemia (ALL). The study aimed to drawthe crucial features of all&fgrp=all&fyrs=all" target="_blank">miRNA in the pathogenesis of ALL. The findings showed that all&fgrp=all&fyrs=all" target="_blank">miRNA expression changes in ALL are typical and involve several signaling pathways. The variations in all&fgrp=all&fyrs=all" target="_blank">miRNA gene expression can lead to the incomplete expression of oncoprotein or tumor suppressor gene (TSG). It seems that all&fgrp=all&fyrs=all" target="_blank">ncRNAs play pivotal roles in the ALL pathogenesis. However, all&fgrp=all&fyrs=all" target="_blank">ncRNAs might be interested as potential diagnostic and prognostic biomarkers in ALL.

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    APA: Copy

    Mazloumi Gavgani, Maryam, Nargesian, Mansooreh, & GHORBIAN, SAEID. (2018). Critical Roles of Non-coding RNAs in Acute Lymphoblastic Leukemia. GENE, CELL AND TISSUE, 5(4), 0-0. SID. https://sid.ir/paper/345199/en

    Vancouver: Copy

    Mazloumi Gavgani Maryam, Nargesian Mansooreh, GHORBIAN SAEID. Critical Roles of Non-coding RNAs in Acute Lymphoblastic Leukemia. GENE, CELL AND TISSUE[Internet]. 2018;5(4):0-0. Available from: https://sid.ir/paper/345199/en

    IEEE: Copy

    Maryam Mazloumi Gavgani, Mansooreh Nargesian, and SAEID GHORBIAN, “Critical Roles of Non-coding RNAs in Acute Lymphoblastic Leukemia,” GENE, CELL AND TISSUE, vol. 5, no. 4, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/345199/en

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