PROTECTIVE EFFECT OF EDIBLE TURMERIC (CURCUMA LONGA LINN.) POWDER ON EARLY HEPATIC INJURY IN DIABETIC RATS

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AMOU OUGHLI TABRIZI B.; MOHAJERI D.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Feyz Medical Sciences Journal Year:2010 | Volume:14 | Issue:3 (SERIAL 55) Page(s): 191-199

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Title

PROTECTIVE EFFECT OF EDIBLE TURMERIC (CURCUMA LONGA LINN.) POWDER ON EARLY HEPATIC INJURY IN DIABETIC RATS

Author(s)

AMOU OUGHLI TABRIZI B. | MOHAJERI D. | Issue Writer Certificate

Keywords

CURCUMA LONGA LINN.Q2

DIABETES MELLITUSQ2

HEPATIC INJURYQ1

RATQ2

Abstract

Background: Hepatic insufficiency is one of the most important consequences of the DIABETES MELLITUS. A wide variety of herbs has been described for the treatment of DIABETES MELLITUS. The aim of present study was to assess the protective effect of turmeric powder on early hepatic injuries in alloxan-induced diabetic RATs.Materials and Methods: Eighty male Wistar RATs were randomly assigned into 4 equal groups. Turmeric powder was added to the food regimen of turmeric treatment groups. At the end of experiment, levels of functional liver markers (AST, ALT and SALP), albumin, total bilirubin and proteins were assessed in the serum. Product of lipid peroxidation (MDA), superoxide dismutase (SOD) activity, catalase (CAT), glutathione peroxidase (GPX) and glutathione reductase (GR) were also assayed in liver hemogenates. Finally, the biochemical findings were matched with histopathological verification. Results: In the diabetic RATs, turmeric powder significantly decreased the levels of serum biomarkers of hepathic injury, TB, and elevated the levels of Alb and TP. Furthermore, turmeric powder significantly decreased the lipid peroxidation and elevated the levels of antioxidant enzymes in the RATs. Conclusion: It seems that turmeric powder has protective effect on early diabetic hepatopathy in experimentally induced diabetic RATs.

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APA: Copy

AMOU OUGHLI TABRIZI, B., & MOHAJERI, D.. (2010). PROTECTIVE EFFECT OF EDIBLE TURMERIC (CURCUMA LONGA LINN.) POWDER ON EARLY HEPATIC INJURY IN DIABETIC RATS. FEYZ, 14(3 (SERIAL 55)), 191-199. SID. https://sid.ir/paper/356839/en

Vancouver: Copy

AMOU OUGHLI TABRIZI B., MOHAJERI D.. PROTECTIVE EFFECT OF EDIBLE TURMERIC (CURCUMA LONGA LINN.) POWDER ON EARLY HEPATIC INJURY IN DIABETIC RATS. FEYZ[Internet]. 2010;14(3 (SERIAL 55)):191-199. Available from: https://sid.ir/paper/356839/en

IEEE: Copy

B. AMOU OUGHLI TABRIZI, and D. MOHAJERI, “PROTECTIVE EFFECT OF EDIBLE TURMERIC (CURCUMA LONGA LINN.) POWDER ON EARLY HEPATIC INJURY IN DIABETIC RATS,” FEYZ, vol. 14, no. 3 (SERIAL 55), pp. 191–199, 2010, [Online]. Available: https://sid.ir/paper/356839/en

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