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Information Journal Paper

Title

THE EVALUATION OF THE ANALGESIC EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF SOLANUM MELONGENA IN SYRIAN MICE USING TAIL FLICK TEST

Pages

  490-500

Abstract

 Introduction: Nowadays, many researches are being conducted in order to evaluate the analgesic effects of different plants which have been used as sedative in traditional medicine.SOLANUM MELONGENA is a plant with different theories about its analgesic effects. In this experimental trial research, the effects of intraperitoneal (IP) injection of hydro-alcoholic extract of SOLANUM MELONGENA were assessed and compared with different doses of MORPHINE and distilled water in Syrian MICE.Methods: The effects of different doses of SOLANUM MELONGENA (1, 10, 100, and 1000 mg/Kg), different doses of MORPHINE sulfate (1, 2, and 4 mg/Kg) and distilled water on acute PAIN was assessed in Syrian MICE. Tail flick latency after IP injection was measured for 75 minutes as the index of PAIN tolerance, using a tail flick apparatus which projects a condensed light stimulus on the animal's tail.Results: Our findings showed that different doses of Solanum increased analgesia index. This effect was more prominent in 45-60 minutes after IP injections which was significantly greater than the control group (p<0.05).Conclusion: Our findings indicated that the hydro-alcoholic extract of SOLANUM MELONGENA produces analgesic effect in a dose- related manner.

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    APA: Copy

    REZAEISADRABADI, M., DASHTI R, M.H., ANVARI, M., FALAH TAFTI, H., & ZANBAGH, S.. (2011). THE EVALUATION OF THE ANALGESIC EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF SOLANUM MELONGENA IN SYRIAN MICE USING TAIL FLICK TEST. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 19(4 (79)), 490-500. SID. https://sid.ir/paper/35846/en

    Vancouver: Copy

    REZAEISADRABADI M., DASHTI R M.H., ANVARI M., FALAH TAFTI H., ZANBAGH S.. THE EVALUATION OF THE ANALGESIC EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF SOLANUM MELONGENA IN SYRIAN MICE USING TAIL FLICK TEST. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;19(4 (79)):490-500. Available from: https://sid.ir/paper/35846/en

    IEEE: Copy

    M. REZAEISADRABADI, M.H. DASHTI R, M. ANVARI, H. FALAH TAFTI, and S. ZANBAGH, “THE EVALUATION OF THE ANALGESIC EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF SOLANUM MELONGENA IN SYRIAN MICE USING TAIL FLICK TEST,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 19, no. 4 (79), pp. 490–500, 2011, [Online]. Available: https://sid.ir/paper/35846/en

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