Cytogenetic findings in couples with fertility problems

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KESHAVARZI FATEMEH; Karimi Behbahani Lida

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Razi Journal of Medical Sciences Year:2019 | Volume:26 | Issue:3 Page(s): 31-39

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Information Journal Paper

Title

Cytogenetic findings in couples with fertility problems

Author(s)

KESHAVARZI FATEMEH | Karimi Behbahani Lida | Issue Writer Certificate

Keywords

Fertility problemsQ1

Cytogenetic studyQ1

Chromosomal aberrationsQ2

Abstract

Background: Chromosomal aberrations can be one of the causes of Fertility problems, including infertility or frequent abortions. Identification of Chromosomal aberrations by clinical diagnostic techniques has been primarily performed through standard karyotyping. In this screening, the prevalence of these disorders were checking in individuals with Fertility problems from west population of Iran. Methods: A prospective Cytogenetic study was conducted on 200 cases (124 women (28. 1± 5) and 76(30. 7± 5) men with Fertility problems and age average 30. 81± 5 for chromosomal abnormalities using routine karyotyping. Results: Types of chromosomal anomalies were observed in 62(31%) individuals (35 and 27 patients with RPL and infertility, respectively). Among the Chromosomal aberrations, the prevalence of translocations, deletions, inversions, duplications and insertions were 40. 32% (25), 22. 6% (14), 17. 74% (11), 9. 7% (6) and 9. 7% (6), respectively. The most abnormal disorder was belonging to chromosomal displacement or translocation (40. 32%). Conclusion: The high prevalence of chromosomal abnormality (31%) in population studied was shown genetic counseling should be providing to the family members to explain the recurrence risk as well as the need for prenatal diagnosis in subsequent pregnancies and management of patients by collected data bank.

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APA: Copy

KESHAVARZI, FATEMEH, & Karimi Behbahani, Lida. (2019). Cytogenetic findings in couples with fertility problems. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 26(3 ), 31-39. SID. https://sid.ir/paper/361052/en

Vancouver: Copy

KESHAVARZI FATEMEH, Karimi Behbahani Lida. Cytogenetic findings in couples with fertility problems. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2019;26(3 ):31-39. Available from: https://sid.ir/paper/361052/en

IEEE: Copy

FATEMEH KESHAVARZI, and Lida Karimi Behbahani, “Cytogenetic findings in couples with fertility problems,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 26, no. 3 , pp. 31–39, 2019, [Online]. Available: https://sid.ir/paper/361052/en

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