The Evaluation of VE-Cadherin Gene Expression in Serum of Iranian Women With Breast Cancer

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ASGHARI A.; ZARRINPOUR V.; DARAEI A.; HAJEBRAHIMI Z.; MOSLEMI D.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2020 | Volume:9 | Issue:4 Page(s): 1829-1936

Download Full-Text

Persian Verion

View:

587

Download:

Cites:

Information Journal Paper

Title

The Evaluation of VE-Cadherin Gene Expression in Serum of Iranian Women With Breast Cancer

Author(s)

Keywords

breast cancerQ1

evaluation of gene expressionQ1

VE-cadherin geneQ1

serum biomarkerQ1

Abstract

Background & Objective: breast cancer is one of the most common cancers and the second leading cause of cancer death in women worldwide, in both developed and developing countries. Vascular endothelial (VE)-cadherin is endothelial specific adhesion molecule located at junctions between endothelial cells and its association with various cancers has been proven. The aim of this study was to evaluate the VE-cadherin gene expression in serum of Iranian women with breast cancer in order to identify a biomarker for its prediction. Materials & Methods: After serum isolation from blood samples of the patients and controls, extraction of RNA and synthesis of cDNA were done. Gene expression was measured using real-time PCR technique. Results: Our results showed that the expression of VE-cadherin was increased significantly in patients compared to control samples. However, there was no relationship between its expression and grade of the tumors. Conclusion: Based on the results of this study, expression of this factor can be used as a marker for study and follow-up of breast cancer patients. Furthermore, considering the role of this factor in angiogenesis and metastasis, it can be used as a target for intervention therapy.

Cites

No record.

References

Cite

APA: Copy

ASGHARI, A., ZARRINPOUR, V., DARAEI, A., HAJEBRAHIMI, Z., & MOSLEMI, D.. (2020). The Evaluation of VE-Cadherin Gene Expression in Serum of Iranian Women With Breast Cancer. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 9(4 ), 1829-1936. SID. https://sid.ir/paper/362533/en

Vancouver: Copy

ASGHARI A., ZARRINPOUR V., DARAEI A., HAJEBRAHIMI Z., MOSLEMI D.. The Evaluation of VE-Cadherin Gene Expression in Serum of Iranian Women With Breast Cancer. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2020;9(4 ):1829-1936. Available from: https://sid.ir/paper/362533/en

IEEE: Copy

A. ASGHARI, V. ZARRINPOUR, A. DARAEI, Z. HAJEBRAHIMI, and D. MOSLEMI, “The Evaluation of VE-Cadherin Gene Expression in Serum of Iranian Women With Breast Cancer,” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 9, no. 4 , pp. 1829–1936, 2020, [Online]. Available: https://sid.ir/paper/362533/en

Related Journal Papers