Comparing the effect of high intensity interval training and continuous training on BDNF, GDNF and NGF in hippocampus of C57BL/6 male mice

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Naghibzadeh Maryam; RANJBAR ROUHOLLAH; TABANDEH MOHAMMAD REZA; HABIBI ABDOLHAMID

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2019 | Volume:26 | Issue:12 Page(s): 1075-1086

Download Full-Text

Persian Verion

View:

503

Download:

Cites:

Information Journal Paper

Title

Comparing the effect of high intensity interval training and continuous training on BDNF, GDNF and NGF in hippocampus of C57BL/6 male mice

Author(s)

Naghibzadeh Maryam | RANJBAR ROUHOLLAH | TABANDEH MOHAMMAD REZA | HABIBI ABDOLHAMID | Issue Writer Certificate

Keywords

Interval trainingQ1

Continuous trainingQ1

NeurotrophinQ1

hippocampusQ2

Abstract

Introduction: Identifying the factors that influence on the uptake of Neurotrophins is an important goal for brain's health and function. There is some evidence that long-term exercise improves brain function. However, the effects of exercise intensities on the brain remain is unclear. Therefore, the purpose of this study was to compare the effects of high intensity interval (HIIT) and Continuous training (CT) on neurotrophic factors gene expression in hippocampus of C57BL/6 mice. Methods: 30 C57BL/6 mice were randomly assigned to the following three groups: control (Con), Interval training (IT), and Continuous training (CT). The mice in the exercise group Were trained to run on the treadmill 5 sessions for 8 weeks. HIIT group performed protocol at 85-90% of maximal work rate for periods of 2 min alternating with 1 min intervals at 50-60% of maximal work rate. CT group performed a continuous exercise protocol at 70-75% of maximal work rate. The expression of BDNF, GDNF, and NGF genes was measured using the Real Time-PCR method in the hippocampus. For statistical analysis of the data was used from SPSS version 16 and the one-way ANOVA method. Results: The result showed that HIIT program significantly increased the mRNA levels of BDNF and GDNF in comparison with CT (p<0. 05), and mRNA level of NGF significantly increased in both groups while no significant differences were observed in NGF concentrations among the HIIT and CT groups (p>0. 05). Conclusion: Our results showed that HIIT had a more neuroprotective effect by improving the expression of the Neurotrophin genes compared to the LICT in the hippocampus.

Cites

No record.

References

No record.

Cite

APA: Copy

Naghibzadeh, Maryam, RANJBAR, ROUHOLLAH, TABANDEH, MOHAMMAD REZA, & HABIBI, ABDOLHAMID. (2019). Comparing the effect of high intensity interval training and continuous training on BDNF, GDNF and NGF in hippocampus of C57BL/6 male mice. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 26(12 ), 1075-1086. SID. https://sid.ir/paper/36420/en

Vancouver: Copy

Naghibzadeh Maryam, RANJBAR ROUHOLLAH, TABANDEH MOHAMMAD REZA, HABIBI ABDOLHAMID. Comparing the effect of high intensity interval training and continuous training on BDNF, GDNF and NGF in hippocampus of C57BL/6 male mice. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;26(12 ):1075-1086. Available from: https://sid.ir/paper/36420/en

IEEE: Copy

Maryam Naghibzadeh, ROUHOLLAH RANJBAR, MOHAMMAD REZA TABANDEH, and ABDOLHAMID HABIBI, “Comparing the effect of high intensity interval training and continuous training on BDNF, GDNF and NGF in hippocampus of C57BL/6 male mice,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 12 , pp. 1075–1086, 2019, [Online]. Available: https://sid.ir/paper/36420/en

Related Journal Papers