Effect of aerobic training and L-carnitine supplementation on some apoptotic factors in diabetic rat liver

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Jabbari Seyyed Esmaeil; GHOLAMI MANDANA; NIKBAKHT HOJJATOLLAH; Shakeri Nader; GHAZALIAN FARSHAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2019 | Volume:26 | Issue:7 Page(s): 131-140

Download Full-Text

Persian Verion

View:

503

Download:

Cites:

Information Journal Paper

Title

Effect of aerobic training and L-carnitine supplementation on some apoptotic factors in diabetic rat liver

Author(s)

Keywords

Aerobic trainingQ1

L-carnitineQ1

DiabetesQ2

Bcl2Q1

BAXQ1

ApoptoseQ1

Abstract

Background: The use of non-enzymatic antioxidants and proper exercise can have a positive effect on decreasing apoptotic side effect. The purpose of this study was to investigate the effect of Aerobic training and consumption of L-carnitine on some of the apoptosis factors in the liver of diabetic rats. Methods: In this experimental study, 45 male Wistar rats (200-300 gr) were randomly divided into six groups: 1) sham group, 2) healthy control group 3) diabetic control group, 4) diabetic group receiving L-carnitine, 5) diabetic group of Aerobic training, 6) diabetic group of Aerobic training and receiving L-carnitine. Rats were diabetic with nicotinic amide and a single dose of STZ of 55 mg / kg body weight. Rats in the L-carnitine group received daily 100 mg of L-carnitine orally. The aerobic exercise protocol done on the treadmill. Results: Combined intervention of aerobic exercise and supplementation of L-carnitine had a significant effect on Bcl2 factor in liver tissue in diabetic rats. However, six weeks of aerobic exercise and supplementation alone do not have a significant effect, six weeks of Aerobic training and combined intervention had significant effect on BAX factor in liver tissue in diabetic rats but supplementation of L-carnitine alone had no significant effect. Conclusion: L-carnitine supplementation intake with regular exercise can have beneficial effects on apoptotic improvement in rats with type 2 Diabetes.

Cites

Twelve weeks of resistance training intervention on serum levels of some apoptosis markers in elderly men

References

Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects

Cite

APA: Copy

Jabbari, Seyyed Esmaeil, GHOLAMI, MANDANA, NIKBAKHT, HOJJATOLLAH, Shakeri, Nader, & GHAZALIAN, FARSHAD. (2019). Effect of aerobic training and L-carnitine supplementation on some apoptotic factors in diabetic rat liver. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 26(7 ), 131-140. SID. https://sid.ir/paper/366076/en

Vancouver: Copy

Jabbari Seyyed Esmaeil, GHOLAMI MANDANA, NIKBAKHT HOJJATOLLAH, Shakeri Nader, GHAZALIAN FARSHAD. Effect of aerobic training and L-carnitine supplementation on some apoptotic factors in diabetic rat liver. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2019;26(7 ):131-140. Available from: https://sid.ir/paper/366076/en

IEEE: Copy

Seyyed Esmaeil Jabbari, MANDANA GHOLAMI, HOJJATOLLAH NIKBAKHT, Nader Shakeri, and FARSHAD GHAZALIAN, “Effect of aerobic training and L-carnitine supplementation on some apoptotic factors in diabetic rat liver,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 26, no. 7 , pp. 131–140, 2019, [Online]. Available: https://sid.ir/paper/366076/en

Related Journal Papers