Evaluation of CTX-M1 and CTX-M15 genes among Klebsiella pneumoniae isolated strains from hospitalized patients in Babol’ s Hospitals

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHEIKHI JAVAD; AMINI AKRAM; EBRAHIMZADEH NAMVAR AMIRMORTEZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2018 | Volume:26 | Issue:5 Page(s): 385-392

Download Full-Text

Persian Verion

View:

492

Download:

Cites:

Information Journal Paper

Title

Evaluation of CTX-M1 and CTX-M15 genes among Klebsiella pneumoniae isolated strains from hospitalized patients in Babol’ s Hospitals

Author(s)

SHEIKHI JAVAD | AMINI AKRAM | EBRAHIMZADEH NAMVAR AMIRMORTEZA | Issue Writer Certificate

Keywords

Klebsiella pneumoniaeQ1

Antibiotic resistanceQ2

CTX-M geneQ2

Beta-lactamaseQ2

PCRQ2

Abstract

Introduction: In the recent decades, the prevalence of Klebsiella pneumoniae Beta-lactamase producing strains has a significant role in nosocomial infections. The aim of this study was to determine the prevalence of different types of CTX-M enzymes among clinical isolates of K. pneumoniae. Methods: In this descriptive cross-sectional study, during six months, K. pneumoniae strains were isolated from laboratory ward of Babol educational hospitals and referred to microbiology laboratory of Babol University of Sciences for final confirmation. Thereafter, antibiogram pattern analysis and the frequency of CTX-M1 and CTX-M15 genes were evaluated. Finally, the results were analyzed by SPSS version 24 software. Results: During six months of this study in 2017, 65 K. pneumoniae and also other bacterial strains such as Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii were collected from laboratory ward of Shahid Beheshti and Ayatollah Rouhani Hospitals. By disc diffusion method, the highest resistance belonged to Amoxicillin (91%), Cefoxitin (45%), Piperacillin (45%) and the lowest belonged to Amikacin (24%) and Imipenem (0%). On the other hand, the percentage of CTX-M1 and CTX-M15 genes were also found to be 62% and 69%, respectively. Conclusion: Regarding to the high prevalence of strains containing broad-spectrum Beta-lactamase enzymes and due to the Antibiotic resistance among K. pneumoniae strains isolated from clinical specimens and also by considering this issue that the current study was the first research for evaluating the frequency of these genes in Babol educational hospitals therefore, it is necessary to adopt appropriate drug regimens to reduce Antibiotic resistances.

Cites

No record.

References

No record.

Cite

APA: Copy

SHEIKHI, JAVAD, AMINI, AKRAM, & EBRAHIMZADEH NAMVAR, AMIRMORTEZA. (2018). Evaluation of CTX-M1 and CTX-M15 genes among Klebsiella pneumoniae isolated strains from hospitalized patients in Babol’ s Hospitals. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 26(5 ), 385-392. SID. https://sid.ir/paper/36634/en

Vancouver: Copy

SHEIKHI JAVAD, AMINI AKRAM, EBRAHIMZADEH NAMVAR AMIRMORTEZA. Evaluation of CTX-M1 and CTX-M15 genes among Klebsiella pneumoniae isolated strains from hospitalized patients in Babol’ s Hospitals. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;26(5 ):385-392. Available from: https://sid.ir/paper/36634/en

IEEE: Copy

JAVAD SHEIKHI, AKRAM AMINI, and AMIRMORTEZA EBRAHIMZADEH NAMVAR, “Evaluation of CTX-M1 and CTX-M15 genes among Klebsiella pneumoniae isolated strains from hospitalized patients in Babol’ s Hospitals,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 5 , pp. 385–392, 2018, [Online]. Available: https://sid.ir/paper/36634/en

Related Journal Papers