ASSOCIATION OF THE INSULIN GENE POLYMORPHISM AND COLORECTAL CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ARKANI MARAL; SAFAEI AKRAM; KARIMI KHATOON; ARBABI ELHAM; ROSTAMI FATEMEH; IMAN MITRA; MOHAMADI PARVANE; HAMZEI ELHAM; VAHEDI MOHSEN; MOHEBI REZA; VAFAEI MOHAMAD; FATEMI REZA; ZALI MOHAMADREZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Koomesh Year:2012 | Volume:13 | Issue:2 (42) Page(s): 172-176

Download Full-Text

Persian Verion

View:

1,522

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION OF THE INSULIN GENE POLYMORPHISM AND COLORECTAL CANCER

Author(s)

Keywords

POLYMORPHISMQ2

COLORECTAL NEOPLASMSQ2

INSULIN RESISTANCEQ1

RS 689Q2

Abstract

Introduction: Some studies have determined that POLYMORPHISM in insulin gene are associated with increased insulin level and resistant to insulin and also cause to increase risk of colorectal cancer (CRC). The goal of this study was to evaluate incidence of the insulin gene POLYMORPHISM (rs689) in an Iranian population and to investigate the role of this POLYMORPHISM in increased risk of CRC.Materials and Methods: Genotyping of the insulin gene were determined in a series of 110 colorectal cancer patients and 110 controls by using polymerase chain reaction and restriction fragment length POLYMORPHISM genotyping assays (PCR-RFLP).Results: P value for genotype AT compared with AA, was 0.052 (OR=1.88, CI=0.99-3.5) and TT versus AA was 0.57 (OR=1.33 CI=0.48-3.6). The results showed that the insulin gene POLYMORPHISM (rs689) is not a predisposing factor to increased risk to CRC (P=0.14). Incidence of mutant allele between patients and controls had no significant differences (OR=1.53 95% CI=0.98-2.39, Pe=0.057).Conclusion: These findings suggest that the insulin gene POLYMORPHISM (rs689) is not associated with increased risk of CRC.

Cites

No record.

References

No record.

Cite

APA: Copy

ARKANI, MARAL, SAFAEI, AKRAM, KARIMI, KHATOON, ARBABI, ELHAM, ROSTAMI, FATEMEH, IMAN, MITRA, MOHAMADI, PARVANE, HAMZEI, ELHAM, VAHEDI, MOHSEN, MOHEBI, REZA, VAFAEI, MOHAMAD, FATEMI, REZA, & ZALI, MOHAMADREZA. (2012). ASSOCIATION OF THE INSULIN GENE POLYMORPHISM AND COLORECTAL CANCER. KOOMESH, 13(2 (42)), 172-176. SID. https://sid.ir/paper/36917/en

Vancouver: Copy

ARKANI MARAL, SAFAEI AKRAM, KARIMI KHATOON, ARBABI ELHAM, ROSTAMI FATEMEH, IMAN MITRA, MOHAMADI PARVANE, HAMZEI ELHAM, VAHEDI MOHSEN, MOHEBI REZA, VAFAEI MOHAMAD, FATEMI REZA, ZALI MOHAMADREZA. ASSOCIATION OF THE INSULIN GENE POLYMORPHISM AND COLORECTAL CANCER. KOOMESH[Internet]. 2012;13(2 (42)):172-176. Available from: https://sid.ir/paper/36917/en

IEEE: Copy

MARAL ARKANI, AKRAM SAFAEI, KHATOON KARIMI, ELHAM ARBABI, FATEMEH ROSTAMI, MITRA IMAN, PARVANE MOHAMADI, ELHAM HAMZEI, MOHSEN VAHEDI, REZA MOHEBI, MOHAMAD VAFAEI, REZA FATEMI, and MOHAMADREZA ZALI, “ASSOCIATION OF THE INSULIN GENE POLYMORPHISM AND COLORECTAL CANCER,” KOOMESH, vol. 13, no. 2 (42), pp. 172–176, 2012, [Online]. Available: https://sid.ir/paper/36917/en

Related Journal Papers